老年急性左心衰竭并心房颤动患者血浆脑钠肽水平检测分析

Analysis of the detection of plasma BNP level in old patients with acute left heart failure and atrial fibrillation

目的 探讨老年人急性左心衰竭并心房颤动与血浆脑钠肽（BNP）水平的关系.方法 86例老年急性左心衰竭患者按心房颤动和窦性心律分为两组,比较两组BNP水平并分析BNP水平与心脏超声参数的相关性.结果 心房颤动组患者血浆BNP（1 320.66±1 546.41） pg/L,明显高于窦性心率组的（989.43±1 042.57） pg/L（t=2.651,P＜0.05）；老年急性左心衰竭并快速心房颤动患者BNP水平与左心房内径（LAD）、左心室舒张末期内径（LVEDD）呈正相关（r=0.723、0.645、均P＜0.01）.结论 老年人急性左心衰竭患合并心房颤动者BNP水平较窦性心率者高,且与LAD、LVEDD有明显相关性.

Objective To observe the correlation between plasma brain natriuretic peptide （BNP） level and atrial fibrillation （AF） in old patients with acute left heart failure. Methods 86 old patients with acute left heart failure were randomly divided into two groups according to AF and sinus rhythm. The plasma BNP level was compared between the two groups. And the relationship between plasma BNP level and the results of ultrasonic cardiography was also assessed. Results Significant difference existed in BNP level between individuals with AF and sinus rhythm [ （ 1 320.66 ＋ 1 546.41 ） pg/L vs （989.43 ＋ 1 042.57 ） pg/L, t = 2.651., P 〈 0.05 ] ; BNP level of the rhythm AF sig- nificantly correlated with LAD and LVEDD （ r = 0. 723,0. 645, all P 〈 0.01 ）. Conclusion The old patients with a- cute left heart failure and AF had higher BNP level than those with sinus rhythm. And BNP level of the rhythm AF sig- nificantly correlated with LAD and LVEDI：J.