七氟烷全凭吸入麻醉在婴幼儿唇腭裂手术的应用

Application of Sevoflurane plus nitrous oxide inhalation anesthesia to infants' cleft palate repair surgery

目的观察七氟烷联合氧化亚氮全凭吸入麻醉在婴幼儿腭裂手术的临床效果。方法将50例腭裂患儿随机均分为两组。K组:氯胺酮+丙泊酚+维库溴铵诱导插管,术中以丙泊酚维持麻醉。S组:七氟烷+维库溴铵静注诱导,术中以七氟烷及氧化亚氮和氧气维持麻醉。结果两组患儿插管均成功,与S组比较,K组诱导后患儿心率增快、血压下降,术中保持较快心率(P<0.05)。术后S组恢复时间早于K组(P<0.05)。结论七氟烷复合氧化亚氮麻醉在婴幼儿腭裂手术中效果理想。

Objective To observe the clinical effect of Sevoflurane plus nitrous oxide inhalation anesthesia on infant cleft palate surgery. Methods Fifty infants with cleft palate were averagely divided into two groups. Group K was induced with Ketamine ＋ Propofol ＋ Vecuronium via endotracheal intubation, and anesthesia was maintained with Propofol. Group S was induced with Sevoflurane ＋ Vecuronium bromide intravenously, and anesthesia was maintained with Sevoflurane plus nitrous oxide. Results Both the two groups were intubated successfully. Compared with Group S, Group K increased in heart rate and decreased in blood pressure after induction, and kept rapid heart rate（ P 〈 0.05 ）. Postoperative recovery was earlier in Group S than in Group K （P 〈 0. 05）. Conclusion Anesthesia of Sevoflurane plus nitrous oxide is effective on infant cleft palate surgery.