超声显像下甲状腺结节内微钙化对乳头状癌的诊断价值

Diagnostic value of sonographic microcalcification to thyroid papillary carcinoma

目的探讨超声显像下甲状腺结节内微钙化对乳头状癌的诊断价值。方法回顾性分析161例甲状腺结节患者超声检查与术后病理结果。结果乳头状癌组微钙化的发生率(88.5%)高于良性结节组(11.9%),差异有统计学意义(P<0.001);超声检查中有微钙化组乳头状癌的发生率(78.0%)高于无微钙化组(5.9%),差异有统计学意义(P<0.001),前者与后者相比发生乳头状癌的相对危险度(Relative Risk,RR)为7.4,即超声显像发现有微钙化组患者获得乳头状癌的危险性是无微钙化组患者的7.4倍。结论超声显像下结节内微钙化是诊断甲状腺癌的良好指标。对超声检查发现甲状腺结节微钙化的患者,应高度警惕甲状腺癌可能。

Objective To investigate the diagnostic value of sonographic microcalcification to thyroid papillary carcino- ma. Methods The results of thyroid nodules uhrasonograhy and pathological of 161 patients were elected and retrospectively analysed. Results The incidence of microcalcification in papillary carcinoma group （88.5%） was higher than the incidence of benign nodules （11.9%）, the difference was statistically significant （P〈0.001）. The incidence of papillary carcinoma in micro- calcification group （78.0%） was higher than non-microcalcification group（5.9%）, the difference was statistically significant （P〈 0.001 ）. The relative risk of the ultrasonic thyroid microcalcification was 7.4,compared with non-microcalcification.Patients with thyroid microcalcification who got the risk of papillary carcinoma was 7.4 times higher than patients with thyroid non-microcalci- fication. Conclusion The detection of thyroid microcalcification by sonography is diagnostically valuable,the possibility of malignancy rises in these cases.