年轻患者发生脑梗死的危险因素分析

Risk factor analysis of occurrence of cerebral infarction in young patients

目的探讨脑梗死患者中年轻患者的临床特点和危险因素。方法连续入选1998年10月～2008年10月入院的1013名患者,根据年龄分为三组:16～44岁(n=64)、45～60岁(n=308)、61～90岁(n=641),收集其脑血管危险因素、人口统计学特点及脑血管影像学结果并进行分析。结果 10年入住院的脑梗死患者只有6.3%的患者年龄<44岁,这些患者以男性为主,多伴有吸烟(P<0.01)、睡眠呼吸暂停(P<0.05)等特征;糖尿病、高血压在年轻患者中相对较少;血脂分析显示年轻患者总胆固醇、低密度脂蛋白胆固醇、高密度胆固醇和甘油三酯值均相对较高(P<0.01);血管影像学检查示年轻患者多为单支血管病变(P<0.01)。结论年轻患者具有明显不同的危险因素组成和血管影像学结果,预后相对较好。

Objective To analyze and explore the clinical characteristics and risk factors of young patients with cere bral infarction.Methods A total of 1013 patients consecutively admitted to our hospital from October 1998 to October 2008 were divided into 3 groups according to age： 16 to 44 years of age（n = 64）,45 to 60 years of age（n = 308）,61 to 90 years of age（n = 641）.Their cerebrovascular risk factors,demographic characteristics and cerebral vascular imag ing results were collected and analyzed.Results Of all the consecutively admitted cerebral infarction patients,only 6.3% were under the age of 44,most were male,most were associated with smoking（P〈0.01）,sleep apnea（P〈0.05） and other features;Diabetes and hypertension were relatively rare among young patients;Lipid analysis showed that the values of total cholesterol,low-density lipoprotein cholesterol,high-density cholesterol and triglyceride of young patients were relatively high（P〈0.01）;Vascular imaging showed that most young patients had single-vessel disease（P〈0.01）.Conclusion Young patients have significantly different risk factors and vascular imaging results,whose progno sis is relatively good.