雾化吸入布地奈德治疗小儿喉气管支气管炎

Budesonide atomization inhalation therapy in the treatment of laryngotra-cheobronchitis in children

目的探讨布地奈德吸入治疗小儿喉气管支气管炎的疗效,评价其临床价值。方法将181例喉气管支气管炎患儿随机分为治疗组和对照组,两组基础治疗相同,包括甲泼尼龙静滴、抗感染、止咳化痰等,治疗组在此基础上给予布地奈德雾化吸入;对治疗前后两组的全身激素应用剂量及治愈率、平均住院时间进行统计学比较。结果治疗组总有效率为94.32%,高于对照组的87.10%,住院天数较对照组缩短1.398d,总有效率及住院天数与对照组相比差异有统计学意义(P<0.05);应用全身激素人均减少1个剂量单位[2mg/(kg·次)]。结论布地奈德雾化吸入治疗小儿喉气管支气管炎可缩短病程,值得临床推广。

Objectieve To discuss the clinical effect of budesonide in treating laryngotracheobronchitis in children,and evaluate its clinical value.Methods 181 cases of children with laryngotracheobronchitis were randomly divided into treatment group and control group.The two groups were received the same treatment including methylprednisolone infusion,anti-infection,relieving cough and phlegm and other.Treatment group was treated with budesonide atomization inhalation.The symptoms disappeared time,systemic corticosteroid dose,total effectivee rate and the average hospitalization days were statistically calculated with two groups.Results The treatment group total effective rate was 94.32%,the control group was 87.10%,hospitalization days was 1.398 days shorter than that of the control group,the difference was significant （P＆lt;0.05）.Besides,systemic application of glucocorticoid reduced 1 doses per capita [2 mg/（kg·time）].Conclusion Budesonide atomization inhalation in the treatment of laryngotracheobronchitis in children can shorten the course of disease and deserves to be performed in more patients.