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骨髓增生异常综合征研究进展 被引量:5

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摘要 骨髓增生异常综合征(MDS)是一组克隆性造血干细胞疾病,其特征是血细胞减少,髓系细胞一系或多系发育异常,无效造血及演变为急性髓系白血病(AML)的风险增高〔1-4〕。MDS的主要病理生理本质是:①起源于造血干细胞的克隆性疾病;②粒系、红系和巨核细胞系一系或多系发育异常;③无效造血。其临床表现主要是外周血一系或多系血细胞计数减少及由此导致的症状和体征,
作者 肖志坚
出处 《临床血液学杂志》 CAS 2013年第4期440-442,共3页 Journal of Clinical Hematology
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参考文献12

  • 1肖志坚,郝玉书.骨髓增生异常综合征的治疗选择[J].中华内科杂志,2007,46(4):265-267. 被引量:7
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  • 4肖志坚.进一步规范我国骨髓增生异常综合征的诊治策略[J].中华血液学杂志,2012,33(7):505-506. 被引量:11
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二级参考文献14

  • 1肖志坚.重视和加强我国儿童骨髓增生异常综合征的研究[J].中国小儿血液,2005,10(3):97-98. 被引量:6
  • 2肖志坚.骨髓增生异常综合征:现况与问题[J].白血病.淋巴瘤,2005,14(4):193-196. 被引量:31
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  • 6Cutler CS, Lee SJ, Greenberg P, et al. A decision analysis of allogeneic bone marrow transplantation for the myelodysplastic syndromes: delayed transplantation for low-risk myelodysplasia is associated with improved outcome. Blood, 2004, 104:579-585.
  • 7List AF, Kurtin S, Roe DJ, et al. Efficacy of lenalidomide in myelodysplastic syndromes. N Engl J Med, 2005,352:549-557.
  • 8Kaminskas E, Farrell A, Abraham S, et al. Approval summary:azacitidine for treatment of myelodysplastic syndrome subtypes.Clin Cancer Res, 2005, 11:3604-3608.
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