谷氨酸对脱氧雪腐镰刀菌烯醇刺激下的断奶仔猪生长性能、血常规及血清生化指标变化的干预作用

Intervention Effects of Glutamic Acid on the Changes of Growth Performance,Blood Routine and Serum Biochemical Indexes in Deoxynivalenol Stressed Weaner Piglets

本文旨在探讨谷氨酸对脱氧雪腐镰刀菌烯醇(DON)刺激下的断奶仔猪生长性能、血常规及血清生化指标变化的干预作用。选用28日龄"杜×长×大"三元杂交断奶仔猪28头,随机分为4组,分别饲喂基础饲粮(NC组)、基础饲粮+4 mg/kg DON(DON组)、基础饲粮+4 mg/kg DON+2%谷氨酸(DG组)和基础饲粮+2%谷氨酸(Glu组),每组7个重复,每个重复1头猪。试验期为37 d,试验结束时测定仔猪的生长性能、脏器指数、血常规和血清生化指标。结果表明:与DON组相比较,DG组仔猪料重比显著下降了8.93%(P<0.05),平均日增重有升高趋势,但差异不显著(P>0.05);肝脏指数、肾脏指数和胰腺指数分别显著降低了10.66%、12.68%和11.71%(P<0.05),脾脏指数显著升高了28.03%(P<0.05);红细胞和血小板数量显著升高(P<0.05),白细胞数量、中性粒细胞百分比、中性粒细胞绝对值、红细胞比积和平均血小板体积有升高趋势,但差异不显著(P>0.05);血清葡萄糖含量、肌酸激酶和谷草转氨酶活性显著降低(P<0.05),总蛋白含量显著升高(P<0.05),谷丙转氨酶活性有降低趋势,但差异不显著(P>0.05)。因此,谷氨酸具有提高DON刺激下的断奶仔猪生长性能并在一定程度上缓解DON应激损伤的效果。

This experiment was conducted to investigate the effects of glutamic acid （Glu） supplementation on the changes of the growth performance, blood routine and serum biochemical indexes in deoxynivalenol （DON） stressed weaner piglets. A total of 28 healthy crossbred （Duroc譒andrace譒argewhite） weaner piglets at 28 days of age were randomly assigned into 4 groups （7 piglets/group）. Piglets in each group were fed a basal diet （NC group）, the basal diet＋4 mg/kg DON （DON group）, the basal diet＋4 mg/kg DON＋2% Glu （DG group） or the basal diet＋2% Glu （Glu group）, respectively. The trial lasted for 37 days. The growth performance, visceral indexes, blood routine and serum biochemical indexes of piglets were measured. The results showed as follows： compared with DON group, feed/gain （F/G） in DG group was significantly reduced by 8.93% （P〈0.05）, and average daily gain （ADG） was increased （P〉0.05）; the indexes of liver, kidney and thymus in DG group were significantly decreased by 10.66%, 12.68% and 11.71% （P〈0.05）, respectively, and spleen index was significantly increased by 28.03% （P〈0.05）; the number of red blood cell and platelet in DG group was significantly increased （P〈0.05）, and the number of white blood cell, percentage of granulocyte, absolute value of granulocyte, hematocrit and mean platelet volume were increased （P〉0.05）; the glucose content, creatine kinase and aspartate aminotransferase activities in serum in DG group were significantly reduced （P〈0.05）, the serum total protein content was significantly increased （P〈0.05）, and the serum glutamic-pyruvic transaminase activity was decreased （P〉0.05）. In conclusions, Glu supplementation may improve the growth performance of weaner piglets and can alleviate the stress response induced by DON.