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富含半胱氨酸61在人皮肤恶性肿瘤中的表达 被引量：3

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摘要 富含半胱氨酸61（Cyr61，又称为CCNI）是结缔组织生长因子（CCN）家族关键成员之一．是一种非常重要的细胞基质调节因子．调控内皮细胞和成纤维细胞的黏附、迁移与增殖，诱导血管发生，参与炎症反应、伤口愈合和组织重塑等过程。近年来．Cyr61与肿瘤的关系越来越受关注。
作者 刘洋 陈骏 李宁丽 汪蓓青 陈向东
机构地区 上海交通大学医学院附属第九人民医院皮肤科 上海交通大学医学院免疫学研究所
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2013年第8期468-470,共3页 Journal of Clinical Dermatology
基金 上海高校青年教师培养资助计划(编号:2011-shjdy33) 上海交通大学医学院附属第九人民医院院基金(编号:JY2011A16)资助项目
关键词 富含半胱氨酸61 恶性肿瘤 皮肤
分类号 R739.5 [医药卫生—肿瘤]
  • 相关文献

参考文献14

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二级参考文献37

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  • 5Huang X, Xiao D W, Xu L Y, et al. Prognostic significance of altered expression of SDC2 and CYR61 in esophageal squamous cell carcinoma [J]. OncolRep, 2009, 21(4): 1123 -1129.
  • 6Lin M T, Zuon C Y, Chang C C, et al. Cyr61 induces gastric cancer cell motility/invasion via activation of the integrln/nuclear factor-kap- paB/cyclooxygenase-2 signaling pathway[ J]. Clin Cancer Res, 2005, 11(16) : 5809 -5820.
  • 7Jiang W G, Watkins G, Fodstad O, et al. Differential expression of the CCN family members Cyr61, CTGF and Nov in human breast cancer [J]. Endocr Relat Cancer, 2004, 11(4) : 781 -791.
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  • 10Lv H, Fan E, Sun S, et al. Cyr61 is up-regulated in prostate cancer and associated with the p53 gene status[ J]. J Cell Biochem, 2009, 106(4) : 738 -744.

共引文献3

同被引文献15

  • 1吴品茹,刘健航.角质形成细胞在色素增加性疾病中的作用研究进展[J].中国美容医学,2007,16(5):703-705. 被引量：4
  • 2Imokawa G. Autoc, rine and paracrine regulation of melanocytes in human skin and in pigmentary disorders [J]. Pigment Cell Re- search, 2004, 17(2): 96-110.
  • 3Wu CS, Yu CL, Wu CS, et al. Narrow-band uhraviolet-B stim- ulates proliferation and migration of cultured melanocytes[J]. Ex- perimental Dermatology, 2004, 13(12): 755-763.
  • 4Hachiya A, Kobayashi A, Yoshida Y, et al. Biphasic expression of two paracrine melanogenic cytokines,stem cell factor and en- dothelin-l, in ultraviolet B-induced human melanogenesis [J]. American Journal of Pathology, 2004, 165(6): 99-109.
  • 5l~y RD. Animal models of ultraviolet radiation (UVR)-induced cutaneous melanoma[J]. Front Biosci, 2002, 7: d1531-d1534.
  • 6yon Thaler AK, Kamenisch Y, Berneburg M. The role of ultraviolet radiation in melanomagenesis[J]. Exp Dermatol, 2010, 9(2): 81-88.
  • 7Sim~es MC, Sousa JJ, Pais AA. Skin cancer and new treatment pe~pectives: a review[J]. Cancer Lett, 2015, 357(I): 8-42.
  • 8Maehara Y, Kabashima A, Koga T, et al. Vascular invasion and potential for tumor angiogenesis and metastasis in gastric cart.i- noma[J]. Surgery, 2000, 128(3): 408--416.
  • 9黄远深,李航,涂平,陈喜雪,杨淑霞,武玲慎,赵俊郁,李雪迎.632例皮肤恶性肿瘤及癌前病变临床分析[J].中华皮肤科杂志,2010,43(7):452-454. 被引量：34
  • 10徐航,江银华.着色性干皮病继发多种皮肤恶性肿瘤患者的护理及心理干预[J].中国实用护理杂志,2013,29(2):39-40. 被引量：1

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临床皮肤科杂志
2013年 第8期

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