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血清脂联素与不稳定心绞痛及其危险因素的相关性 被引量:8

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摘要 目的分析血清脂联素(APN)在不稳定心绞痛诊疗中价值及APN与不稳定心绞痛(UA)危险因素的相关性。方法回顾分析老年冠状动脉粥样硬化性心脏病患者临床资料;比较UA组与健康对照组年龄、性别、C反应蛋白(CRP)、心肌肌钙蛋白I(cTnI)、APN、总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)及空腹血糖(FPG)浓度;分析UA组APN与冠心病(CAC)危险因素的相关性。结果 UA组血TC水平与对照组相比,差异无统计学意义(P>0.05);UA组血TG、LCL-C水平、CRP、cTnI水平均高于对照组(P<0.05);UA组血APN水平低于对照组(P<0.001);UA组血清APN与LDL、TG、CRP及FPG呈负相关(P<0.05)。结论血清APN在UA患者血液中呈现低水平,且血清APN与LDL、TG、CRP及FPG呈负相关;APN降低与cTnI升高是UA发生的独立风险因素。血清APN具有和常规血液学指标共同提示CAC发生、发展的价值。
作者 张俊
出处 《中国老年学杂志》 CAS CSCD 北大核心 2013年第13期3082-3083,共2页 Chinese Journal of Gerontology
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