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米力农治疗心脏术后肺动脉高压的疗效观察 被引量:3

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摘要 目的探讨米力农治疗心脏术后肺动脉高压的疗效。方法选择我院自2009年9月至2011年1月接受心脏病手术的中度肺动脉高压患者共20例。20例患者均在术前行超声心动图检查确诊为中度肺动脉高压(肺动脉收缩压50~70 mmHg,Pp/Ps为0.55~0.75)。术后两组患者均给予多巴胺3~10μg/(kg min)A组为对照组,未予米力农治疗。B组为鲁南力康(米力农)治疗组(山东鲁南制药厂生产),首剂量25~75μg/kg静脉注射(>10min),继以0.25~0.75μg/(kg min)静脉泵入。观察术前及术后两小时两组患者肺动脉压力(收缩压PAP)体动脉压力(收缩压SAP)肺动脉压/主动脉压体动脉力(PP/Ps)氧合指数(OI)的差异。结果 B组治疗后的PAP、PP/Ps与治疗前比较明显降低,差异有统计学意义。P<0.05;而SAP较治疗前明显升高,差异有统计学意义。说明米力农与多巴胺在升高体循环压力方面有协同作用,提高心肌收缩力,增加心排量。OI较治疗前升高,差异有统计学意义。说明米力农治疗后,对肺氧合功能有较明显的改善。结论米力农治疗心脏术后肺动脉高压有效,值得临床推广。
作者 徐栋
出处 《中国医药指南》 2013年第19期200-202,共3页 Guide of China Medicine
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