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重组人干扰素α-1b联合锌剂治疗小儿秋季腹泻的临床观察 被引量:1

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摘要 目的探讨重组人干扰素α-1b联合锌剂治疗治疗小儿秋季腹泻疗效。方法 142例患儿随机分为两组,均为71例,对照组静脉点滴病毒唑注射液和口服思密达。治疗组肌肉注射重组人干扰素α-1b和口服葡萄糖酸锌颗粒,比较疗效和部分临床指标。结果治疗组疗效明显优于对照组,呕吐停止时间、退热时间、住院时间、腹泻停止时间明显短于对照组(P<0.05)。结论重组人干扰素α-1b联合锌剂治疗秋季腹泻疗效显著,值得推广。
作者 段瑞强
出处 《中国医药指南》 2013年第19期495-496,共2页 Guide of China Medicine
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  • 1方鹤松 魏承毓 段恕诚 等.腹泻病疗效判断标准的补充建议.中国实用儿科杂志,1998,13(6):384-384.
  • 2杨宝峰 苏定冯.药理学[M].北京:人民卫生出版社,2005.444-445.
  • 3盛晓阳,沈晓明.锌缺乏与儿童感染性疾病[J].中华儿科杂志,2007,45(3):164-166. 被引量:157
  • 4沈晓明,王卫平.儿科学[M].7版.北京:人民卫生出版社,2007:404.

二级参考文献22

  • 1Rahman MJ, Sarker P, Roy SK, et al. Effects of zinc supplementation as adjunct therapy on the systemic immune responses in shigenosis.Am J Clin Nutr, 2005, 81:495-502.
  • 2Bobat B, Coovadia H, Stephen C, et al. Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomized double-bllnd placebo-controlled trial. Lancet, 2005, 366 : 1862-1867.
  • 3Shankar AH, Prasad AS. Zinc and immune function: the biological basis of altered resistance to infection. Am J Clin Nutr, 1998,68:447S-463S.
  • 4Beck FWJ, Kaplan J, Fine N, et al. Decreased expression of CD73 (ecto-5' -nucleotidase) in the CD8^+ subset is associated with zinc deficiency in human patients. J Lab Clin Med, 1997, 130:147-156.
  • 5Rink L,Kirchner H. Zinc-altered immune function and cytokine production. J Nutr, 2000, 130:1407S-1411S.
  • 6Fraker PJ. Roles for cell death in zinc deficiency. J Nutr, 2005, 135:359-362.
  • 7Fraker PJ. Roles for cell death in zinc deficiency. J Nutr, 2005, 135:359-362.
  • 8Bray TM, Bettger WJ. The physiological role of zinc as an antioxidant. Free Radio Biol Med, 1990, 8:281-291.
  • 9Osendarp SJ, Santosham M, Black RE, et al. Effect of zinc supplementation between 1 and 6 mo of life on growth and morbidity of Bangladeshi infants in urban slums. Am J Clin Nutr, 2002, 76:1401-1408.
  • 10Hotz C, Brown KH. Identifying populations at risk of zinc deficiency: the use of supplementation trials. Nutr Bey, 2001,59:80-84.

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