急性冠状动脉综合征患者大血小板比率与冠状动脉病变的相关性

Platelet-large cell ratio in patients with acute coronary syndrome

目的:研究大血小板比率(P-LCR)与急性冠状动脉(冠脉)综合征(ACS)发病及病变程度之间的关系。方法:选取ACS患者136例,分为ST段抬高心肌梗死(STEMI)组和非ST段抬高ACS(UA/NSTEMI)亚组,选择同期非缺血性胸痛患者60例为对照组。入院后空腹采静脉血检测血常规、出凝血时间、血小板聚集率。结果:P-LCR在ACS两个亚组均显著高于对照组(P<0.01),但不同冠脉病变程度差异无统计学意义(P>0.05)。结论:P-LCR在ACS患者中增高。

Objective：To investigate whether platelet-large cell ratio （P-LCR） was associated with the onset and severity of acute coronary syndrome （ACS）. Method： We selected 136 patients with ACS. 60 patients with non-cardiac chest pain were served as control. P-LCR, platelet aggregation rate （PAR）, and biochemical indexes were measured by standard methods. Result： Patients with ACS had higher P-LCR （P〈0.01） compared with con- trol group, while there were no significant differences in severity ACS （P〉0.05）. Conclusion：P-LCR enhanced in patients with ACS.