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应更新对散发性脑淀粉样血管病的认识 被引量:1

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摘要 散发性脑淀粉样血管病(sporadiccerebralamyl—oidangiopathy,sCAA或CAA)是老年人常见的脑小血管病,病理特征为进展性淀粉样蛋白.B(A[5)沉积在脑微小血管及毛细血管的血管壁上,与阿尔茨海默病不同,CAA的AB主要由更可溶的、40个氨基酸片段(A[340)组成。过去临床上认为CAA只表现为脑叶出血,目前随着先进的结构和(或)分子影像学技术的应用,对CAA的病理生理及临床表现的认识有了划时代的发展,但神经科医生对它的认识仍不足和滞后,故也缺乏其患病率和发病率的资料。
作者 李新 王纪佐
出处 《中华医学杂志》 CAS CSCD 北大核心 2013年第27期2103-2105,共3页 National Medical Journal of China
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