降低鸡传染性鼻炎灭活疫苗(A型)副反应试验

Trials to Reduce the Side Effect of Inactivated Infectious Coryza (Serotype A) Vaccine

鸡传染性鼻炎是由副鸡嗜血杆菌引起的一种鸡的急性呼吸系统疾病。该病分布于世界各地,常造成严重的经济损失,如有并发感染和其他应激因素,则损失更大。鸡传染性鼻炎灭活疫苗预防鸡传染性鼻炎可起到良好的效果。生产鸡传染性鼻炎灭活疫苗(A型)一批,进行安全检验时,出现严重副反应,影响了产品质量。为了查找副反应原因以及如何降低副反应,做一系列试验,为下一步疫苗生产打下良好的基础。

Chicken infectious coryza of chicken is an acute respiratory disease caused by Haemophilus paragallinarum.The disease spreads in the world, causing serious economic losses. With concurrent infection and other stress factors, the loss is greater. Chicken infectious coryza inactivated vaccine against chicken infectious coryza played a important role. We used a batch of inactivated avian infectious coryza （ type A） vaccines for safety inspection.But serious side effects were observed, affecting the quality of the products. In order to find out the reason and how to reduce the side reaction, a series of tests were carryed out so as to lay on foundation for the production of the vaccine.