浅析急性高容量血液稀释用于神经外科手术患者的可行性与安全性

Analysis of Acute High-capacity Hemodilution Neurosurgery Feasibility and Safety of Patients

目的探讨急性高容量血液稀释用于神经外科手术的可行性与安全性。方法选取该院神经外科开颅手术患者60例,随机分为A组(AHH组)和B组(对照组),比较诱导前(TBase),机械通气后(To)及输液30min后(T30)患者的各项指标。结果全麻诱导后,两组患者的cI明显降低(P<0.05);AHH后,A组患者cI与CVP明显升高(P<0.05),SVRI与SVV明显下降(P<0.05),CERO2与SjvO2在AHH前后以及组间差异不明显(P>0.05)。结论急性高容量血液稀释用于神经外科手术,不干扰患者脑氧供需平衡,是安全可行的。

Objective To study the feasibility of acute hypervolemic hemodilution for patients in Department of neurosurgery operation and safetyFull of.Methods From 2011 July-2012 year in July 60 cases in Department of Neurosurgery of our hospital surgical operation patients,randomly divided into A group（AHH group） and group B（control group）,compare before induction（T Base）,after mechanical ventilation（To） and 30 min（T30） infusion after the index patients.Results After induction of anesthesia,two groups of patients with cI were significantly decreased（P0.05）;AHH,cI and CVP in A group were significantly increased（P 0.05）,SVRI and SVV significantly decreased（P0.05）,CERO2 and SjvO2 before and after AHH and no obvious difference between groups（P0.05）.Conclusion Acute hypervolemic hemodilution in Department of neurosurgery operation,does not interfere with cerebral oxygen supply and demand balance,is safe and feasible.