宫颈癌术后同步放化疗辅以中药内服的临床观察及毒副反应分析

Clinical effect and toxicity reaction of radiotherapy and chemotherapy combined with Chinese medicine in treating cervical cancer

目的研究宫颈癌术后同步放化疗辅以中药内服的临床疗效及毒副反应。方法选择宫颈癌术后患者作为研究对象,随机分为给予中药内服联合同步放化疗的观察组以及单独给与同步放化疗的对照组,观察免疫功能指标、肿瘤内分泌指标以及不良反应例数。结果观察组的VEGF水平及不良反应例数均明显低于对照组,CD3+、CD4+/CD8+、NK、TNF-α含量及sFlt-1水平明显高于对照组。结论同步放化疗辅以中药内服能够改善治疗效果、增强免疫功能、减少毒副反应,具有积极的临床价值。

Objective To study the clinical efficacy and toxicity reaction of radiotherapy and chem- otherapy combined with Chinese medicine in treating cervical cancer. Methods cervical cancer patients were enrolled and randomly divided into observation group given radiotherapy and chemotherapy combined with Chinese medicine and control group given radiotherapy and chemotherapy. Then immune function, endo- crine tumor index and cases of adverse reactions were observed. Results the VEGF level and cases of ad- verse reactions were less than contral group; CD3＋ , CD4 ＋/CD8 ＋ , NK, TNF- ct and sFlt-1 levels were sig- nificantly higher than control group. Conclusion radiotherapy and chemotherapy combined with TCM have positive clinical value for it can improve clinical effect and immune function, reduce toxicity reaction.