复方冰硼冲洗液体外抑菌效果的评价

Evaluation on antimicrobial efficacy of Fufang Bingpeng irrigant: An in vitro study

目的评价纯中药制剂复方冰硼冲洗液和冰硼冲洗液对4种牙髓病原菌的体外抗菌活性。方法采用琼脂稀释法,测定复方冰硼冲洗液和冰硼冲洗液对4种厌氧病原菌牙龈卟啉单胞菌、中间普氏菌、具核梭杆菌和粪肠球菌的最小抑菌浓度(MIC)和最小杀菌浓度(MBC)。结果 2种冲洗液对4种厌氧病原菌均有抗菌作用,复方冰硼冲洗液的抗菌性优于冰硼冲洗液。粪肠球菌的抗药能力明显强于其余3种菌株。结论纯中药制剂复方冰硼冲洗液具有良好的抗菌性,作为根管冲洗液可能是有优势的。

Objective To evaluate the antimicrobial efficacy of Fufang Bingpeng irrigant and Bingpeng irrigant on four endodontic pathogen bacteria. Methods The agar dilution method was used to observe the antimicrobial activity of Fufang Bingpeng irrigant, Bingpeng irrigant against four selected endodontic pathogen bacteria（Porphyromonas gingi- va!is, Prevotella intermedius, Fusobacterium nucleatum, Enterococcus faecalis）. Minimum inhibitory concentration and minimum bactericidal concentration was examined. Results Two irrigants had the antimicrobial activity against the anaerobic microorganisms. The antimicrobial efficacy of Fufang Bingpeng irrigant was better than that of Bingpeng irri- gant. Compared with others, Enterococcus faecalis had the strongest resistance. Conclusion Fufang Bingpeng irrigant has good antibacterial activity. As a root canal irrigant, Chinese medicine alteratives might be advantageous.