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Vγ9Vδ2 T细胞免疫治疗多发性骨髓瘤的研究进展 被引量:1

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摘要 多发性骨髓瘤(MM)是骨髓中浆细胞恶性增生的疾病,患者在诊断时多伴有溶骨性病变和剧烈疼痛。近年来MM的免疫治疗方面取得新进展,研究证实,Vγ9Vδ2 T细胞可通过直接杀伤肿瘤细胞和抑制破骨细胞形成阻断MM患者疾病进展。笔者结合Vγ9Vδ2 T细胞相关基础研究及临床试验,就其在MM免疫治疗的激活与杀伤作用方面作一综述。
出处 《国际输血及血液学杂志》 CAS 2013年第4期442-445,共4页 International Journal of Blood Transfusion and Hematology
基金 国家自然科学基金(编号81272628) 福建省自然科学基金(编号2011J05064)
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