慢性阻塞性肺疾病中医“肺虚络瘀”病机理论探析

Theorerical Discusstion on Pathomechanism of Deficiency of Lung and Obstructed Collaterals of Chronic Obstruetive Pulmonary Disease

根据中医络病理论,结合慢性阻塞性肺疾病(COPD)病理生理特点,首次提出"肺虚络瘀"是COPD基本病机。认为病位在肺,其与脾肾关系密切;病机为"肺虚络瘀"并重,肺虚贯穿始终,为病机关键,虚源于肺、脾、肾三脏,肺虚外延为肺肾气虚、阴虚或气阴两虚为本虚一方,脾虚为中流砥柱,是致病之本;络瘀外延气滞、痰、湿、虚、毒皆致血瘀肺络而致病,是致病之标。立足病机,提出"补肺化痰通络"之法。为中医临床防治本病提供新思路。

It was first to pose that the cause and pathomechanism is the deficiency of lung and the obstructed collaterals, based on the TCM collateral disease theory, connected the pathophysiological characteristics of COPD. We proposed the idea that the disease locates in the lung with close relation to the spleen and kidney. The pathomechanism should be the deficiency of lung and the obstructed collaterals with the deficiency of lung through the whole disease process, which is the key to the pathomechanism, and the deficiency is originated from the lung, spleen and kidney. The deficiency of the lung includes the qi deficiency, yin deficiency or both qi and yin deficiency of the lung and kidney. The deficiency of the spleen is the root of the disease. The obstructed collaterals includes the qi stagnation, phlegm, dampness, deficiency, toxin, which is the main cause of the disease. According to pathomechanism, we prosed the method of tonilying the lung, reducing phlegm and dredging collaterals. It provided a new approach to the preventioil and control of the disease for the doctor of traditional Chinese medicine clinic.