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帕瑞昔布钠用于腹腔镜下阑尾切除术后超前镇痛的效果观察 被引量:3

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摘要 帕瑞昔布钠是特异性环氧合酶2(COX-2)抑制药,临床上用于中度或重度术后急性疼痛的治疗.在全身麻醉下行腹腔镜下阑尾切除术,虽然手术创伤小、术后恢复快,但苏醒期躁动率较高,仍存在术后疼痛,尤其是术后24 h内.帕瑞昔布钠可有效抑制外周和中枢COX-2表达,减少外周和中枢前列腺素的合成,抑制痛觉超敏,提高痛阈.本研究观察诱导时,静脉给予帕瑞昔布钠对腹腔镜下阑尾切除术后的镇痛效果及苏醒质量.
出处 《中国医药》 2013年第8期1189-1189,1191,共2页 China Medicine
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参考文献6

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共引文献62

同被引文献39

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