泮托拉唑预防骨科术后消化道失血的疗效观察

The curative effect of pantoprazole to prevent postoperative enteron blood loss of orthopedics

目的:探讨泮托拉唑预防骨科术后应激性溃疡消化道失血的疗效。方法:2008年3月～2012年11月,116例骨科手术患者随机分为两组:A组为泮托拉唑注射液预防组59例,B组为西咪替丁注射液预防组57例,评价术后应激性溃疡消化道失血情况。结果:A组1例(1.69%)出现应激性溃疡消化道失血,B组21例(36.84%)出现应激性溃疡消化道失血,A、B组间比较差异具有统计学意义(P<0.05)。结论:泮托拉唑能有效预防骨科术后应激性溃疡消化道失血。

Objective：To approach the curative effect of pantoprazole to prevent postoperative enteron blood loss of orthopedics.Methods：Between March 2008 and November 2012,116 postoperative patients of orthopedics were divided randomely into two groups.Group A：59 patients were treated with pantoprazole,Group B：57 patients were treated with cimetidine,postoperative enteron blood loss were appraised.Results：Group A：1 patient （1.69%）occurrenced postoperative enteron blood loss,Group B：21 patient （36.84%）occurrenced postoperative enteron blood loss,the difference rate of two groups have statistical significance （P0.05）.Conclusion：Pantoprazole can effective prevent postoperative enteron blood loss of orthopedics.