鹅不食草醇提取物抑菌作用研究

Antibacterial activities of ethanol extract from Centipeda minima

目的:通过抑菌试验了解中药鹅不食草乙醇提取物的抗菌活性。方法:试验采用纸片扩散法测定乙醇提取物对福氏志贺菌、金黄色葡萄球菌、变形杆菌、枯草芽胞杆菌、铜绿假单胞菌、大肠埃希菌、藤黄微球菌、酿酒酵母的抗菌活性。采用试管比浊法测定其最小抑菌浓度。结果:鹅不食草提取物除福氏志贺菌、铜绿假单胞菌、酿酒酵母无抑菌活性外,对其余菌株均有抑菌作用,尤其对金黄色葡萄球菌的抑菌活性显著。结论:鹅不食草有较好的抑菌效果,在临床抗菌消炎方面有极大地优势。

Objective： To explore the antimicrobial activity of traditional Chinese medicine （TCM） Centipeda using bacteriostatic test. Methods： The antimicrobial activity of Centipeda ethanol extraction to to Shigella bacteria, Staphylococcus aureus, Proteusbacil- lus vulgaris, Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Micrococcus luteus and Saccharomyces cerevisiae were stud- ied by means of the disc diffusion. The minimum inhibitory concentration （MIC） was analyzed by tube nephelometry. Results： Centi- peda ethanol extractions have bacteriostasis except to Shigella bacteria, Pseudomonas aeruginosa, Saccharomyces cerevisiae and have significant antibacterial activity to staphylococcus anreus. Conclusion Centipeda： minima has better bacteriostasis effect, and has great advantages in the clinical antibacterial anti -inflammatory.