期刊文献+

非治疗阿尔茨海默病的药物对阿尔茨海默病预防与治疗的最新进展

下载PDF
导出
摘要 阿尔茨海默病(AD)是以认知功能障碍和记忆损害为主要临床特征的神经退行性疾病,AD的发生隐匿,早期不易被发现,且病程呈渐进性发展,其典型临床症状的产生给家庭和社会都带来了诸多问题。目前已成为世界上继心脏病、肿瘤和脑卒中之后的第四大死亡原因,其早期诊断及防治成为一个世界性难题。本文就非治疗AD的药物对AD治疗及防治的最新进展予以综述。
出处 《实用心脑肺血管病杂志》 2013年第8期13-16,共4页 Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
  • 相关文献

参考文献24

  • 1Tolppanen AM, Lavikainen P, Solomon A, et al. History of medically treated diabetes and risk of alzheimer disease in a nationwide ease - con- trol study [J]. Diabetes Care, 2013 Jan 22. [ Epub ahead of print].
  • 2Ohara T, Doi Y, Ninomiya T, et al. Glucose tolerance status and risk of dementia in the community: the Hisayama study [ J ]. Neurology, 2011, 77 (12): 1126-1134.
  • 3Denner LA, Rodriguez-Rivera J, Haidacher SJ, et al. Cognitive en- hancement with rosiglitazone links the hippocampal PPART and ERK MAPK signaling pathways [J]. J Neurosci, 2012, 32 (47) : 16725 - 16735.
  • 4van Eersel J, Ke YD, Liu X, et al. Sodium selenate mitigates tau pa- thology, neurodegeneration, and functional deficits in Alzheimer's dis- ease models [J]. Proc Nad Acad Sci USA, 2010, 107 (31) : 13888-13893.
  • 5Craft S, Baker LD, Montine TJ, et al, Intranasal insulin therapy for Alzheimer disease and amnestic mild cognitive impairment: a pilot clini- cal trial [J]. Arch Neurol, 2012, 69 (1): 29-38.
  • 6Roberts RO, Geda YE, Knopman DS, et al. Cardiac disease associat- ed with increased risk of nonanmestic cognitive impairment: stronger effect on women [J]. JAMA Neurol, 2013, 28:1 -9.
  • 7Baskys A, Cheng JX. Pharmacological prevention and treatment of vas- cular dementia: approaches and perspectives [ J]. Exp Gerontol, 2012, 47 (11): 887-891.
  • 8Hajjar I, Brown L, Mack WJ, et al. Impact of Angiotensin receptor blockers on alzheimer disease neumpathology in a large brain autopsy se- ries [J]. AmhNeuml, 2012, 69 (12): 1632-1638.
  • 9Dodel R, Romlnger A, Bartenstein P, et al. Intravenous immunoglob- ulin for treatment of mild - to - moderate Alzheimer's disease: a phase 2, randomised, double - blind, placebo - controlled, dose - finding trial [J]. Lancet Neurol, 2013, 12 (3): 233-243.
  • 10Vidal EI, Fukushima FB, VaUe AP, et al. Unexpected improvement in levedopa - induced dyskinesia and on - off phenomena after introduc- tion of memantine for treatment of Parkinson's disease dementia [ J]. J Am Geriatr Soc, 2013, 61 (1): 170-172.

二级参考文献39

  • 1Long-xuanLI,Jia-peiDAI,Li-qiangRU,Guang-fuYIN,BinZHAO.Effects of tanshinone on neuropathological changes induced by amyloid β-peptide(1-40)injection in rat hippocampus[J].Acta Pharmacologica Sinica,2004,25(7):861-868. 被引量:12
  • 2刘中华,胡海涛,冯改丰,赵志英,毛乃颖.天麻素对Aβ25-35诱导的Alzheimer病细胞模型的保护作用[J].四川大学学报(医学版),2005,36(4):537-540. 被引量:29
  • 3李桂英,唐功香,李永华.半夏白术天麻汤治疗阿尔茨海默病[J].临床和实验医学杂志,2006,5(5):602-602. 被引量:11
  • 4张勇,席刚明,周少华.天麻及其成分对神经系统的作用[J].国际中医中药杂志,2006,28(5):268-271. 被引量:53
  • 5Malone RE. China's chanees,China's choices in global tobacco control. Tob Control, 2010,19 : 1 -2.
  • 6Gu D,Kelly TN,Wu X,et al. Mortality attributable to smoking in China. N Engl J Med,2009,360:150 -159.
  • 7Anstey KJ ,von Sanden C,Salim A,et al. Smoking as a risk factor for dementia and cognitive decline: a meta-analysis of prospective studies. Am J Epidemiol,2007,166:367 -378.
  • 8Cataldo JK, Prochaska JJ, Glantz SA. Cigarette smoking is a risk factor for Alzheimer's Disease:an analysis controlling for tobacco industry affiliation. J Alzheimers Dis, 2010, 19:465 -480.
  • 9Timmer NM, van Dijk L, van der Zee CE, et al. Enoxaparin treatment administered at both early and late stages of amyloid beta deposition improves cognition of APPswe/PS1dE9 mice with differential effects on brain A beta levels. Neurobiol Dis, 2010,40:340 -347.
  • 10Gazdzinski S, Durazzo TC, Yeh PH, et al. Chronic cigarette smoking modulates injury and short-term recovery of the medial temporal lobe in alcoholics. Psychiatry Res, 2008, 162:133 -145.

共引文献16

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部