期刊文献+

骨质疏松与良性阵发性位置性眩晕之间的关系 被引量:6

原文传递
导出
摘要 目的良性位置性眩晕的病因目前尚不明确,有研究发现患者年龄越大,耳石退化的程度越严重,本研究的目的是探讨骨质疏松与特发性良性位置性眩晕之间的关系。方法对429名已确诊为特发性良性位置性眩晕的老年女性患者进行腰椎及股骨骨密度检测。最终所得T值与没有眩晕病史的500名正常老年女性进行比较,观察T值大小是否有统计学差异。结果在429名良性位置性眩晕患者中341名(79.5%)出现骨质疏松,且T值明显较低。结论骨质疏松与特发性良性位置性眩晕的发病有关。首先,雌激素水平下降导致骨量调节物质的减少,这可能影响了耳石的内部结构及/或耳石之间的相互连结及与凝胶基质的连结。其次,钙重吸收的增加可能会使内耳淋巴液的游离钙离子浓度上升,从而使得异位脱落的耳石难以自行溶解。
出处 《中华全科医学》 2013年第10期1589-1591,共3页 Chinese Journal of General Practice
  • 相关文献

参考文献10

  • 1Vibert D, Kompis M, Hausler R. Benign paroxysmal positional vertigo in older women may be related to osteoporosis and osteopenia[ J]. Ann Otol Rhinol Laryngol,2003,112(10) :885-889.
  • 2Jang YS,Gu TW,Bae WY,et al. Results of bone mineral density measurement in women patients with idiopathic benign paroxysmal positional vertigo [ J ]. Korean J Otolaryngol-Head Neck Surg, 2007,50 (9): 750-754.
  • 3Hollick RJ, Reid DM. Role of bisphosphonates in the management of postmenopausal osteoporosis:an update on recent safety anxieties[ J]. Menopause Int,2011,17(2) :66-72.
  • 4Yang H,Zhao X,Xu Y,et al. Matrix recruitment and calcium sequestration for spatial specific otoconia development[ J]. PLOS One,2011,6(5):e20498.
  • 5Harada Y, Kasuga S, Mori N. The process of otoconia formation in guinea pig utricular supporting cellsf J]. Acta Otolaryngol, 1998,118(1):74-79.
  • 6Campos A,Crespo PV,Garcia JM,et al. The crystalline pattern of calcium in different topographical regions of the otoconial membrane. An electron probe and spectroscopic diffraction study[J]. Acta Otolaryngol,1999,119(2) :203-206.
  • 7Balsamo G, Avallone B, Del Genio F,et al. Calcification processes in the chick otoconia and calcium binding proteins : patterns of tetracycline incorporation and calbindin-D28K distribution [ J]. Hear Res, 2000,148(1-2) :l-8.
  • 8Takeda S. Novel regulatory mechanism of bone metabolism[ J]. Nihon Rinsho,2011,69(7) : 1209-1214.
  • 9Rachner TD,Khosla S,Hofbauer LC. Osteoporosis:now and the future [J].Lancet,2011,377(9773) :1276-1287.
  • 10Zucca G, Valli S, Valli P,et al. Why do benign paroxysmal positional vertigo episodes recover spontaneously? [J]. J Vestib Res, 1998,8(4):325-329.

同被引文献37

引证文献6

二级引证文献50

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部