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肠癌肝转移综合治疗的现状和展望

Current Situation and Prospect of Multi-modality Treatment for Colorectal Liver Metastases
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摘要 结直肠癌肝转移是影响结直肠癌预后的重要因素,目前提倡综合治疗,以手术为核心,辅以化疗、靶向治疗、局部治疗(放疗、介入治疗等)。随着新药的研发,新技术的应用,个体化治疗、转化治疗的开展,其预后显著改善。而生物心理社会医学模式同样使患者获益。本文对结直肠癌肝转移的综合治疗进行综述。 Liver metastases is the main fact affecting prognosis of colorectal cancer. The multi--modality treatment is now advocated. Surgery is the major treatment, combined with chemotherapy, targeted therapy and local therapy (radiothera- py, interventional therapy). With the development of new medications, application of new techniques, individualized treat- ment and conversion therapy, the prognosis significantly improves. Patients also benefit from the bio-- psycho-- social medical model. We will summarize the multidisciplinary therapy of colorectal liver metastases.
出处 《医学与哲学(B)》 2013年第7期18-22,共5页 Medicine & Philosophy(B)
关键词 结直肠癌 肝转移 综合治疗 colorectal cancer, liver metastases, multi-- modality treatment
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参考文献44

  • 1Jemal A,Bray F,Center M M,et al. Global Cancer Statistics[J]. CACancer J Clin,2011,61 (2):69 - 90.
  • 2Kemeny N,Fata F. Arterial, ponal,or systemic chemotherapy forpa-tients with hepatic metastasis of colorectal carcinoma[J]. J Hepato-biliary Pancreat Surg,1999 ,6(1) : 39 - 49.
  • 3Jemal A,Siegel R, Ward E, et al. Cancer statistics, 2007 [J], CACancer J Clin,2007,57(1) :43 -66.
  • 4Vigano L,Russolillo N,Ferrero A,et al. Evolution of Long -TermOutcome of Liver Resection for Colorectal Metastases: Analysis ofActual 5-Year Survival Rates over Two Decades[J], Ann Surg0ncol,20l2,19(6) =2035-2044.
  • 5Arru M, Aldrighetti L,Castoldi R,et al. Analysis of prognostic fac-tors influencing long-term survival after hepatic resection for me-tastatic colorectal cancer[J]. World J Surg, 2008 ,32(1) : 93 - 103.
  • 6Foster J H,Berman M M. Solid Liver Tumors. Major Problem inclinicalsurgery[M], Philadelphia, PA: W. B. Saunders company,1977:1-342.
  • 7Fong Y,Cohen A M,Fortner J G,et al. Liver resection for colorec-tal metastases[J]. J Clinoncol,1997,15(3):938 - 946.
  • 8Fong Y,Former J ,Sun R L,et al. Clinical score for predicting recur-rence after hepatic resection for metastatic colorectal cancer:analy-sis of 1001 consecutive cases [ J]. Ann Surg, 1999,230 ( 3 ) : 309-318.
  • 9结直肠癌肝转移诊断和综合治疗指南(V2010)[J].中华胃肠外科杂志,2010,13(6):457-470. 被引量:60
  • 10Gustavsson B. Simultaneous Surgery for Primary Colorectal Cancerand Metastatic Lesions? [J]. Scand J Gastroenterol, 2012*47(3):269-276.

二级参考文献14

  • 1Arru M, Aldrighetti L, Castoldi R, etal. Analysis of prog nostic factors influencing long-term survival after hepatic resection for metastatic colorectal cancer [J]. World J Surg, 2008, 32(1): 93-103.
  • 2Kanso F, Adam R. Surgery of hepatic metastasis in colorectalcancers[J]. RevPrat, 2010, 60(8): 1108-1110.
  • 3Folprecht G, Gruenberger T, t3echstein WO, et al. Tumour response and secondary reseetability of colorectal liver metas tases following neoadjuvant chemotherapy with cetuximah: the CELIM randomised phase 2 trial [J]. Lancet Oncol, 2010, 11(1), 38-47.
  • 4Welch S, Spithoff K, Rumble RB, et al. Bevacizumab combined with chemotherapy for patients with advanced colorec- tal cancer: a systematic review Ⅱ. Ann Oncol, 2010, 21 (6) : 1152-1162.
  • 5Raoul JL, Van Laethem JL, Peeters M, etal. Cetuximab in combination with irinotecan/5-fluorouracil/folinic acid (FOLFIRI) in the initial treatment of metastatic colorectal cancer: a multicentre two-part phase Ⅰ/Ⅱ study [J]. BMC Cancer, 2009, 9: 112.
  • 6Stang A, Fischbach R, Teichmann W, et al. A systematic review on the clinical benefit and role of radiofrequency ablation as treatment of coloreetal liver metastases[J]. Eur J Cancer, 2009, 45(10)= 1748-1756.
  • 7Poultsides GA, Servais EL, Saltz LB, et al. Outcome of primary tumor in patients with synchronous stage 1V colorectal cancer receiving combination chemotherapy without surgery as initial treatment[J]. J Clin Oncol, 2009, 27(20): 3379-3384.
  • 8Aslam MI, Kelkar A, Sharpe D, et al. Ten years experienceof managing the primary tumours in patients with stage IV colorectalcancers [J]. Int J Surg, 2010, 8(4): 305-313.
  • 9Stillwell AP, Buettner PG, Ho YH. Meta-analysis of survival of patients with stage IV colorectal Cancer managed with surgical resection versus chemotherapy alone[J]. World J Surg, 2010, 34(4): 797-807.
  • 10I.in BS, Ziogas A, Seery TE, etal. Role of surgical resection among chemotherapy-treated patients with coloreetal cancer stage Ⅳ disease.. A survival analysis[J]. J Clin Oncol, 2011, 29(15): 3564.

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