舒芬太尼和七氟烷不同剂量组合对创伤患者心肌损伤的协同保护作用

Myocardial Protective Effects of Different Doses Combination of Sufentanil and Sevoflurane Post-conditioning on Traumatic Patients

创伤失血性休克患者在接受液体复苏和输血治疗时,由于再灌注可导致心肌和心脏功能进一步受损。在再灌注前应积极采取临床措施以保护心脏。阿片类药物和吸入麻醉药物后处理对创伤失血性休克患者心肌缺血-再灌注损伤具有良好的保护作用。此研究中,笔者将不同剂量的舒芬太尼和七氟烷联合应用,通过对患者心肌酶检测相比较,发现两种药物组对后处理是否对失血性休克患者心肌缺血-再灌注损伤具有协同保护作用。

When traumatic hemorrhagic shock patients received fluid resuscitation and blood transfusions therapy, myocardium and cardiac functions of them will be further damaged for ischemia--reperfusion. Active clinical measures should be taken to protect hearts. Both opioids and inhalation anesthetic drugs post-conditioning can protect myocardium from ische- mia--reperfusion injury in traumatic hemorrhagic shock patients. In this study, different doses combination of sufentanil and sevoflurane were used on hemorrhagic shock patients. Results of myocardial enzyme test showed that there was synergy of sufentanil combins with sevoflurane post-conditioning on myocardial ischemia-reperfusion injury of hemorrhagic shock patients.