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麻醉对先天性心脏病修复术患儿大脑发育影响的研究进展 被引量：2

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摘要 每年大约有10万例患儿需在出生后第1年于全身麻醉下行先天性心脏病修补术。手术技术、体外循环、麻醉、重症监护管理等大大提高了患儿的长期存活率。随着存活率的提高及越来越复杂的手术过程，神经系统异常的风险及患儿的生活质量和神经损伤的预后备受关注。这些患儿的神经发育多数是正常的，但有20％～50％的患儿有神经功能缺损和发育不全，其原因是多方面的，如脑发育健全、紫绀型患儿的手术时期、脑区域长期处于低血氧饱和度、
作者 梁园园 郑宏
机构地区 新疆医科大学第一附属医院麻醉科
出处 《临床麻醉学杂志》 CAS CSCD 北大核心 2013年第7期721-722,共2页 Journal of Clinical Anesthesiology
基金 高等教育博士学科点专项科研基金联合资助课题(20126517110005) 新疆自治区重点学科项目[新教研(2010)7号]
关键词 先天性心脏病 全身麻醉 大脑发育 患儿 修复术 长期存活率 神经系统异常 神经功能缺损
分类号 R726.1 [医药卫生—儿科]
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参考文献18

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二级参考文献9

  • 1岳云.如何看待麻醉监测的临床与科学研究[J].临床麻醉学杂志,2007,23(7):586-587. 被引量：10
  • 2Avidan MS,Zhang L,Burnside BA,et al.Anesthesia awareness and the bispectral index.N Eng J Med,2008,13:1097-1108.
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  • 5Leslie K,Myles PS,Forbes A,et al.Recovery from bispectral index-guided anaesthesia in a large randomized controlled trial of patients at high risk of awareness.Anaesth Intensive Care,2005,33:443-451.
  • 6Schraag S,Bothner U,Gajraj R,et al.The performance of e-lectroencephalogram bispectral index and auditory evoked potential index to predict loss of consciousness during propofol infusion.Anesth Analg,1999,89:1311-1315.
  • 7Iannuzzi M,Iannuzzi E,Rossi F,et al.Relationship between Bispectral index,electroencephalographic state entropy and effect-site EC50 for propofol at different clinical endpoints.Br J Anaesth,2005,94:492-495.
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  • 9McDermott NB,VanSickle T,Motas D,et al.Validation of the bispectral index monitor during conscious and deep sedation in children.Anesth Analg,2003,97:39-43.

共引文献4

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二级引证文献8

临床麻醉学杂志
2013年 第7期

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