深圳市城乡女性人乳头瘤病毒感染相关因素调查

Relevant factors to female human papillomavirus infection in city and rural areas of Shenzhen

目的研究城市和农村女性人乳头瘤病毒（HPv）感染相关因素的差异。方法2009—2010年对深圳市城乡10000名有性生活女性行HPV感染危险因素调查，并以3种方法检测人群HPV感染情况。结果总人群平均年龄38．9岁，HPV阳性率为33．3％，其中城市（特区内、外）人群HPV阳性率分别为35．8％和30．2％，农村人群为33．8％。特区内人群HPV感染相关因素主要为人工流产史、多性伴及配偶长期外出；特区外人群HPV感染相关因素主要为多次人工流产、多性伴及使用避孕套避孕；农村人群HPV感染相关因素为多次人工流产和吸烟。结论城乡人群HPV感染相关因素具有差异。其中城市人群主要与多性伴相关，性生活使用避孕套有防护作用；吸烟对农村女性人群具有危险性；而多次人工流产为城乡女性人群HPV感染共同的危险因素。

Objective To study the differences of relevant factors to human papillomavirus （HPV） infection between urban and rural women. Methods 10 000 sexually active women from Shenzhen city and rural areas were interviewed with questionnaire on risk factor to HPV infection and screened for cervical cancer, using 3 kinds of HPV test. Results Average age of the study population was 38.9, with prevalence rates of HPV infection among the total population, people in SSEZ （Shenzhen Special Economic Zone）, out of SSEZ, and rural areas were 33.3%, 35.8%, 30.2%, and 33.8% respectively. Relevant factors to HPV infection in SSEZ were those mainly having had history of abortion, having more sexual partners in lifetime and husbands who work outside the area. Relevant factors to HPV infection out of SSEZ were those mainly having had more episodes of abortion, more sexual partners in lifetime and using condom more than other contraceptives. Relevant factors to HPV infection in rural area were： having more abortions and smoking behavior. Conclusion There were some differences of relevant factors to HPV infection between urban and rural women. In urban area, having had more sexual partners in lifetime played a very important role in contracting HPV infection while condom use for contraception seemed to be a protective factor. In the rural areas, smoking was a risk factor for HPV infection, to some extent. Having had more episodes on abortion showed as a common risk factor to both urban and rural females, on HPV infection.