ICU病房常见致病菌分布及耐药性分析

The distribution of common pathogenic bacteria and drug resistance analysis in ICU ward

目的：了解ICU病房病原菌分布及对抗菌药物的耐药状况。方法：对我院ICU病房两年结果阳性病原菌，病原菌药物敏感性进行分析。结果：分离758株病原菌，其中革兰阴性菌占75．5％，革兰阳性菌占24．5％；前5位病原菌为大肠埃希菌、肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌、鲍曼不动杆菌分别占20．05％、17．55％、13．72％、7．12％、4．88％；细菌产ESBLs的阳性率大肠埃希菌60．3％，肺炎克雷伯菌33．1％，MRCNS78．8％，不动杆菌多重耐药率明显高于铜绿假单胞菌。结论：ICU病房的病原菌耐药严重，检测细菌分布及耐药性变化有利于临床合理使用抗生素。

Objective ： To investigate the distribution of pathogenic bacteria and the drug sensitivity of antimicrobial resistance condition in ICU. Methods ： The positive pathogens and drug sensitivity of pathogenic bacteria from ICU in our hospital were analyzed.Results ： Separate 758 strains of pathogenic bacteria, among whicr the gram negative bacteria accounted for 75.5% and gram positive bacteria accounted for 24.5%. The top 5 pathogens bacteria were Escherichia coli, KlebsieUa pneumoniae, Pseudomonas aeruginosa, Staphylococcus aureus and Acinetobacter baumannii. They were accounted for 20.25%, 17.55%, 13.72%, 7.12%, 4.88%. respectivery The positive rate of ESBLs producing bacteria were Escherichia coli 60.3%, KlebsieUa pneumoniae 33.1%, MRCNS 78.8%, the rate of bacteria multiple resistant of acinetobacter is obviously higher than that of Pseudomonas aeruginosa.Conclusions ： The problem of the pathogen resistance of ICU were serious. It＇s very important to understand the change of bacteria distribution and drug resistance, and it is helpful to select antibiotics correctly.