期刊文献+

奈达铂同步IMRT治疗中晚期食管癌的临床观察 被引量:2

下载PDF
导出
摘要 目的:探讨奈达铂联合IMRT治疗中晚期食管癌的近期疗效和毒副反应。方法:64例中晚期食管癌患者随机分为奈达铂同步放疗组(观察组,n=32)和单纯放疗组(对照组,n=32),两组放疗均采用IMRT,照射剂量60~66Gy。观察组:奈达铂30mg/m2,1次/周,直至放疗结束。结果:观察组有效率78.1%,对照组有效率53.1%。所有毒副反应均可耐受,经相应处理均恢复正常。结论:奈达铂同步IMRT治疗中晚期食管癌近期疗效较好,毒副反应轻。
机构地区 中山市人民医院
出处 《中外医学研究》 2013年第22期51-52,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
  • 相关文献

参考文献6

  • 1Cooper J S, Guo M D, Herskovic A, et al.Chemoradiotherapy of locally advanced esophageal cancer: long -term follow-up of a prospective randomizedtrial(RTOG 85-01)[J].JAMA, 1999, 281(17): 1623-1627.
  • 2王新强,程秀祯,王世伟,代培永,林祥来,杨怀泮.放疗联合PF方案同步治疗中晚期食管癌[J].中华放射肿瘤学杂志,2005,14(3):215-215. 被引量:52
  • 3温珍平,冯铁虹.食管癌的内科化疗现状及进展[J].现代肿瘤医学,2010,18(4):830-833. 被引量:18
  • 4吴立洲,刘汉山,蔡炜.放疗同步应用奈达铂治疗中晚期食管癌的临床观察[J].临床肿瘤学杂志,2009,14(3):245-246. 被引量:12
  • 5Sasaoka M, Fuwa N, Matsumoto A, et al.Alternating chemotherapy for oropharyngeal cancer[J]Gan To Kagaku Ryoho, 2000, 27(14): 2217- 2221.
  • 6Kanzawa F, Koizumi F, Koh Y, et al.In vitro synergisdc interactions between the cisplatin analogue nedaplatiri and the DNA topoisomerase I inhibitor irinotecan and the mechanism of this interaction[J].Clinic Cancer Res, 2001, 7(1): 202-209.

二级参考文献26

  • 1樊青霞,李鑫,吴欣爱,王留兴,王瑞林.诺维本联合顺铂治疗食管鳞癌的临床观察[J].癌症进展,2004,2(2):109-111. 被引量:10
  • 2郑育举,肖大伟,郑毓武.健择在36例期食管癌术后辅助化疗中的应用[J].福建医药杂志,2004,26(3):14-15. 被引量:6
  • 3乔学英 周道安.中晚期食管癌放射治疗配合卡铂的远期疗效[J].中华放射肿瘤学杂志,1997,6(2):118-119.
  • 4Parkin DM,Bray F,Ferlay J,et al.Global cancer statistics,2002[J].CA Cancer J Clin.2005,55(2):74-108.
  • 5Medical Research Council of esophageal Cancer Working Party.Surgical resection with or without preoperative chemotherapy in esophageal cancer:A randomized controlled trial[J].Lancet,2002,359(9319):1727-1733.
  • 6Urshel JD,Vasan H,Blewett CJ.A Meta-analysis of randomized conrolled trials that compared neoadjuvant chemotherapy and surgery to surgery alone for respectable esophageal cancer[J].Am J Surg,2002,183(2):274-278.
  • 7Malthaner R,Fenlon D.Preoperative chemotherapy for respect-able thoracic esophageal cancer[J].The Cochrane Database of Systemic Reviews,2003,Issue 4.Art No.CD001556.
  • 8Kaklamanos IG,Walker GR,Ferry K,et al.Neoadjuvant treatment for respectable cancer of the esophagus and the gastro-esophageal junction:a meta-analysis of randomized clinical trials[J].Ann Surg Oncol 2003,10(7):754-758.
  • 9Forshaw MJ,Gossage JA,Mason RC.Neoadjuvant chemotherapy for esophageal cancer:the need for accurate response prediction and evaluation[J].The Surgeon,2005,3(6):373-382.
  • 10Leonard GD,Reilly EM.Post-operative chemotherapy improves disease-free survival,but not overall survival in people with esophageal squamous cell carcinoma[J].Cancer Treat Rev,2004,30(5):473-477.

共引文献77

同被引文献12

引证文献2

二级引证文献3

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部