乳腺癌新辅助化疗疗效评价的相关研究

Evaluation of response to neoadjuvant chemotherapy in breast cancer

术前新辅助化疗已成为局部进展期乳腺癌患者的标准化治疗方法，随着新辅助化疗在临床治疗中的广泛应用，疗效评价显得尤为重要。如何能无创、及时、准确、有效地评价化疗疗效已成为临床研究的重点。目前临床上通常采用临床触诊、影像学测量及病理学检查等方法，同时对乳腺癌生物学因子的研究也在迅速展开。现将各种评价方法的应用现状作一综述。

Preoperative neoadjuvant chemotherapy has become the standardized treatment for patients with locally advanced breast cancer. With the wide application of neoadjuvant chemotherapy in clinic, evaluation of response to neoadjuvant chemotherapy seems increasingly important. How to evaluate the curative effect of chemotherapy timely, accurately, effectively and noninvasively has become the focus of clinical research. At present, clinical palpation, radiographic measurement and pathological examination are usually used in clinic, and the study of breast cancer biology factor is also rapidly spread. The application status of different evaluation methods of neoadjuvant chemotherapy were reviewed in this article.