门控心肌灌注显像相位分析在心血管疾病左室机械不同步中的应用

The application of phase analysis of gated myocardial perfusion imaging to assess left ventric-ular mechanical dyssynchrony in cardiovascular disease

左室机械不同步与心功能不全的严重程度密切相关，准确评估左室机械不同步，对预测心脏不良事件、指导心脏再同步治疗及预后评估具有重要的临床意义。门控心肌灌注显像（GMPI）相位分析是一项定量评估左室机械不同步的新技术。通过一次GMPI检查既可以得到局部心肌血流灌注的定量指标，同时还能定量分析左室心功能和左室收缩协调性，在研究心血管疾病左室机械不同步及预后评估中具有广阔的应用前景。该文着重对GMPI相位分析在心血管疾病诊疗中的应用进展进行综述。

Left ventricular mechanical dyssynchrony is closely related to the severity of cardiovascular disease, it is essential to assess left ventricular mechanical dyssynehrony accurately for early prediction of adverse cardiac events and prognosis assessment of the cardiac resynchronization therapy. As a new technology to assess left ventricular mechanical dyssynehrony, the phase analysis of gated myocardial perfusion imaging （ GMPI ） can get both quantitative indicators of regional myocardial perfusion, evaluation of regional myocardial viability and scar tissue, as well as quantitative analysis of left ventricular function and left ventricular mechanical synchrony, it has broad application prospects in cardiovascular disease to assess left ventricular mechanical dyssynchrony and prognosis assessment. This review mainly described the applications of GMPI phase analysis in the cardiovascular disease.