地奥司明治疗包皮环切术后水肿的临床研究

Clinical Study of Diosmin Tablets on Treatment of Postoperative Edema of Circumcision

目的:探讨地奥司明对包皮环切术后包皮水肿的临床疗效。方法:选择拟行包皮环切术患者130例,随机分成2组,治疗组65例,术后在常规换药、抗感染治疗的基础上口服地奥司明片1周,对照组65例,术后仅给予常规换药、抗感染治疗。术后随访观察2周,记录水肿发生情况及消退时间。结果:治疗组4例出现轻度水肿,对照组15例出现水肿,治疗组水肿消退时间明显缩短。2组水肿发生率及消退时间均有显著性差异。结论:地奥司明对于防治包皮环切术后水肿具有明显疗效。

Objective：To observe the therapeutic and preventive effect of the diosmin on postoperative edema of circumcision. Meth- ods：One hundred thirty patients who underwent circumcision were divided into two groups ,treatment group（ n = 65 ） and control group（ n = 65 ）. Patients in the treatment group were administrated with diosmin tablets for 7 days in addition to antibiotics and dressing change, where as controls were only given antibiotics and dressing change. Results：All the patients were followed up two weeks after operation, and the incidence of postoperative edema, the swelling time were recorded. Results In the postoperative edema of circumcision, the treat- ment group and the control group were in 4 eases and 15 cases respectively. The difference and swelling time between the two groups was significant （ P 〈 0.05 ）. Conclusion： The diosmin has a remarkable effect on treatment of postoperative edema of circumcision.