摘要
脂肪乳在肠外营养中有着十分重要的作用,能够提供能量和必需脂肪酸。目前临床上常用脂肪乳为50%中链三酰甘油(MCT)和50%长链三酰甘油(LCT)做物理混合的脂肪乳。结构脂肪乳是一种新型脂肪乳,是在同一个甘油分子骨架上同时具有MCT和LCT的重组三酰甘油。目前结构脂肪乳在动物实验及肠内营养研究中已得到肯定。肠外营养的研究中,结构脂肪乳对正氮平衡影响肯定,在代谢指标方面体现出更快的血浆清除率及加速氧化,但有的研究结果显示与普通的脂肪乳间差异无统计学意义。
Fat emulsion plays an important role in parenteral nutrition,it＇ s considered as a source of calories and essential fatty acids.Physically mixed 50% medium-chain triglyceride and 50% long-chain triglyceride is available in most Chinese hospitals now.Structured triglyceride（STG）,a new type of fat emulsion,is defined as rearranged triglycerides that have both medium-chain fatty acid and long-chain fatty acid on the same glycerol backbone.STG is well accepted as a safe source of triglycerides in animal and human enteral nutrition studies.In parenteral nutrition trials,STG has a better effect on nitrogen balance,however,in terms of metabolic parameters,some studies have revealed faster clearance and greater oxidation for STG,whereas others revealed no marked difference comparing with common lipid emulsions.
出处
《医学综述》
2013年第15期2732-2734,共3页
Medical Recapitulate
关键词
结构脂肪乳
肠外营养
临床研究
Structured triglyceride
Parenteral nutrition
Clinical trials
