宫颈癌术中保留卵巢移位标记并阴道延长的临床分析

Clinical Analysis on Ovarian Transposition Mark and Vaginal Prolonged Retention in Cervical Cancer Operation

目的探讨年轻宫颈癌患者在宫颈癌根治术中保留一侧或双侧卵巢移位标记同时延长阴道的临床价值。方法选择2005年1月至2012年6月间在陕西电子409医院妇产科收治的28~40岁的Ⅰa~Ⅱa宫颈癌患者22例为观察组,观察组患者在宫颈癌根治术中保留一侧或双侧卵巢并移位标记同时阴道延长;取同期38~45岁常规行宫颈癌根治术的22例患者作为对照组。观察两组患者手术历时时间、术中出血、术后并发症及术前、术后性激素水平的变化、阴道情况（长度、弹性、湿润度）、性生活质量等,进行比较。结果①观察组和对照组手术均成功,两组手术时间、术中出血比较差异无统计学意义（t=1.1497,0.3837,P〉0.05）。②观察组术前、术后6个月的卵泡刺激素、雌二醇水平比较,差异无统计学意义（t=2.0166,0.8187,P〉0.05）;观察组和对照组术后6个月的卵泡刺激素水平比较,差异有统计学意义（t=16,0532,P〈0.001）。③术后6个月观察组的阴道长度、性生活质量显著优于对照组（t=37.8000,P〈0.05;χ2=10.1149,P〈0.01）。结论宫颈癌根治术中保留卵巢移位标记同时延长阴道对年轻宫颈癌患者的生活质量有明显改善。

Objective To investigate the clinical value of retaining one or both ovaries transposition mark of young cervical cancer patients and prolonging vagina during cervical cancer operation.Methods From January 2005 to June 2012 in Department of Obstetrics and Gynecology,Shaanxi Electronic 409 Hospital,22 patients between the age of 28-40 in Ia-Ⅱ a stage of cervical cancer were selected as the observation group,whose ovarian unilateral or bilateral transposition marks were retained and vagina was extended in cervical cancer radical operation;at the same time,22 patients between the age of 38-45 who had routine cervical cancer radical surgery were selected as the control group.The length of operation time,bleeding in operation,post-operative complications,and sex hormone levels changes after surgery and vaginal conditions（length,elasticity,moist degree）,and sexual life quality of the two groups were observed and compared.Results ①The operation of observation and control groups were all successful,and the operation time and inoperative bleeding of the two groups had no significant differences（t = 1.1497,0.3837,P 0.05）.②Follicle-stimulating hormone,estradiol levels of the observation group before surgery and six months after surgery had no statistically significant difference（t = 2.0166,0.8187,P 0.05）;follicle-stimulating hormone levels of the observation group and control group six months after surgery had statistically significant difference（t = 16,0532,P 0.001）.③Vaginal conditions and sexual life quality of the observation group was significantly better than the control group six months after surgery with a significant difference（t = 37.8000,P 0.05;χ2 = 10.1149,P 0.01）.Conclusion Reservation of ovarian transposition mark and vaginal extension in radical hysterectomy of the young patients with cervical cancer can significantly improve their life quality.