82例剖宫产术中氯胺酮和丙泊酚全麻诱导的应用疗效分析

82 cases of cesarean section ketamine and propofol anesthesia induction efficacy analysis applications

目的观察胺碘酮联合丙泊酚全麻诱导在剖宫产手术中的临床疗效。方法将2009年3月—2012年2月入住该院的82例足月妊娠产妇随机分成观察组和对照组,其中观察组41例,采用氯胺酮联合丙泊酚全麻诱导麻醉,对照组41例,采用腰硬联合麻醉,记录并比较两组患者术中各时间段BP、HR、SPO2、RR变化、镇静效果评分、麻醉至胎儿出生时间间隔(ID)、Apgar评分。结果两组患者在切皮时及胎儿分娩时平均动脉压(MAP)、HR、RR均较术前有所上升,但差异无统计学意义(P>0.05),关闭腹膜时两组患者SPO2均有不同程度下降,但差异无统计学意义(P>0.05);观察组在切皮时、胎儿分娩时的镇静效果评分明显高于对照组(P<0.05);观察组给药后至产儿娩出时间间隔明显少于对照组(P<0.05),Apgar评分相比差异无统计学意义(P>0.05)。结论剖宫产术中采用氯胺酮联合丙泊酚全麻诱导效果好,值得在临床上予以推广。

Objective To observe the amiodarone propofol induction of anesthesia for caesarean section surgery clinical efficacy. Methods The March 2009 February 2012 Check our hospital 82 cases were randomly divided into full-term pregnancy maternal observation group and control group, in which the observation group 41 cases, the use of ketamine and propofol anesthesia induction of anesthesia, the control group 41 cases, the use of epidural anesthesia, recorded and compared two groups of patients undergoing each time period BP, HR, SPO2, RR changes, sedation score, anesthesia to birth interval （ID）, Apgar score. Results The patients in the skin incision and fetal birth mean arterial pressure （MAP）, HR, RR compared with preoperative increased, but no significant difference （P 〉0.05）, close the peritoneum when both groups of patients SPO2 there are different degrees of decline, but no significant difference （P 〉0.05） ; observation group incision, the fetus during childbirth sedative effect score was significantly higher （P 〈 0.05） ; observation group to births delivered time after administration interval was significantly less than the control group （P 〈 0.05） ; Apgar score was no significant difference （P 〉0.05）. Conclusion Cesarean section with ketamine and propofol anesthesia induction effect, to be worthy of promotion in clinical practice.