两种安瓿开启法药液质量的差异性研究

Study on the effect of injection quality with their ampoule opened by two methods

目的探讨两种安瓿开启法对药液质量的的影响。方法实验组消毒平镊敲断安瓿,对照组垫无菌纱布掰断安瓿各80支。抽取药液进行72h细菌培养;并检测药液中直径≥2、5、10、15、35、50μm微粒数。结果两组药液均无细菌生长;药液中除直径≥50μm微粒数外,其余直径微粒数两组差异有统计学意义(P<0.01)。结论消毒平镊敲断安瓿法可显著减少药液微粒数,优于垫无菌纱布掰断法。

Objective To supply the objective evidences for nurses to open ampoules safely in clinical work through the study on injection quality with their ampoule opened by two methods.Methods The 80 ampoules in study group were opened by sterilized forceps.The 80 ampoules in control group were opened by nurses held with asepsis gauze.Biological detection and microparticles detection were compared.Results There were no bacteria grown in the two groups.The numbers of microparticles with diameter 2、5、10、15、35μm in study group were obviously less than that in control group.Conclusion The microparticles in the injections opened ampoules by sterilized forceps were much less than that with asepsis gauze.The method with sterilized forceps to open ampoules was better than with asepsis gauze.