摘要
甲状腺激素对心血管系统的重要作用得到广泛认识。多数患者心脏手术后出现低三碘甲状腺原氨酸状态,称为甲状腺功能正常病态综合征。对成人、儿童的心脏手术和心脏移植术后纠正低三碘甲状腺原氨酸状态的大量研究证实,三碘甲状腺原氨酸治疗可改善术后血流动力学和心脏功能,但对患者的病死率和预后的影响不明确。因此,三碘甲状腺原氨酸是否作为常规药物的使用需要更多的临床研究来证实。
It has been established that the thyroid hormone has important effects on the heart and peripheral vascular system.Open heart operations usually result in a low triiodothyronine（T） 3 state,called non-thyroidal illness syndrome.Numerous studies correcting the low T3 state after adult and pediatric heart surgery and heart transplantation have confirmed that T3 treatment can improve postoperative hemodynamics and heart function.However,the influence on the patient’s mortality is not clear.This review discusses whether T3 could be used as a regular treatment needed to confirm by more clinical trials.
出处
《心血管病学进展》
CAS
2013年第4期478-481,共4页
Advances in Cardiovascular Diseases
关键词
甲状腺激素
甲状腺病态综合征
心脏手术
thyroid hormone
non-thyroidal illness syndrome
cardiac surgery
