摘要
支架作为一种药物控制释放平台,通过控制药物释放、输送成为减少新生内膜过度增生的一种有效方式,但当支架被应用于复杂心脏解剖结构和临床情况下,支架内再狭窄仍有可能发生,表明药物洗脱支架仍需改进。现综述药物洗脱支架参数间的相互关系,以及这些参数在抗再狭窄过程中扮演了何种角色,以期为降低再狭窄提供参考。
Stent as a drug controlled release platform,is an effective means of reducing neointimal hyperplasia by controling drug release and convey.Drug-eluting stent（DES） restenosis may still occur especially when stents are used in complex anatomical and clinical scenarios which indicated that still need to be improved.This article summarizes the relationship in the drug-eluting stent parameters and discuss these parameters play what role in anti-restenosis process and order to provide a reference for reducing restenosis.
出处
《心血管病学进展》
CAS
2013年第4期520-523,共4页
Advances in Cardiovascular Diseases
关键词
药物支架
再狭窄
内膜增生
生物相容性
drug-eluting stent
restenosis
neointimal hyperplasia
biocompatibility
