不同期别矽肺患者并发脑梗塞的特点分析

Analysis of clinical characteristics of sillicosis patients complicated with cerebral infarction at different stages

目的探索不同期别的矽肺患者并发脑梗塞的特点及其机制。方法 68例矽肺并发脑梗塞患者按照矽肺期别分为三组。通过t检验或χ2检验比较三组患者入院时血压、左心室射血分数、颈部血管的血流速度和重度狭窄例数、分水岭梗塞例数;统计分水岭梗塞的发生率。结果Ⅰ期和Ⅱ期组间入院时收缩压和颈部血管血流速度无显著差异;Ⅲ期和其它两组之间差异有统计学意义(P<0.05)。入院时舒张压和左心室射血分数三组间差异均有统计学意义(P<0.05);而颈部血管重度狭窄和分水岭梗塞组间均无显著差异。分水岭梗塞总体发生率为16.2%,Ⅱ期患者最低而Ⅲ期最高。结论矽肺患者并发分水岭梗塞的比例可能较高,主要体现在Ⅲ期患者并发率明显增高。

Objective To research the clinical characteristics and mechanism of sillicosis patients complicated with cerebral in- faretion at different stages. Methods 68 sillicosis patients complicated with cerebral infarction were divided into three groups based on different sillicosis stages. Their blood pressure on admission, left ventricular ejection fraction, blood flow velocity and quantity of severe stenosis of carotid arteries and quantity of cerebral watershed infarction were detected by T test or X2 test. Results There was no signifi- cant difference between the stage Ⅰ and Ⅱ groups about systolic blood pressure on admission and blood flow velocity of carotid arteries, but there was significant difference between the stage Ⅲ group and the other two groups about over indexes （ P 〈 0. 05 ）. There was signifi- cant difference on diastolic blood pressure on admission and left ventricular ejection fraction among the three groups （P 〈0. 05 ）, but the quantity of carotid arteries severe stenosis and cerebral watershed infarction showed no obvious difference among the three groups. The total incidence of cerebral watershed infarction was 16. 2%, of which the stage Ⅱ group was the lowest and the stage In group was the highest. Conclusion The incidence of watershed infarct in sillicosis patients complicated with cerebral infarction is relative high, which mainly exists in patients at stage Ⅲ.