两种口服液治疗儿童急性支气管炎的疗效对比

Comparison of two kinds of oral solution in the treatment of children with acute tracheobronchitis

目的对比分析愈酚伪麻与盐酸氨溴索口服溶液治疗儿童急性支气管炎的疗效。方法选取我院收治的297例急性支气管炎患儿随机分成实验组(148例)与对照组(149例)。实验组口服愈酚伪麻溶液,对照组口服盐酸氨溴索溶液,所有患儿的疗程均为1周。对比分析两组的疗效及不良反应。结果治疗3 d,7 d后,实验组各项症状与综合积分与白细胞数明显优于对照组(P<0.05);治疗7 d后,实验组的疗效要显著优于对照组(P<0.05);两组发生不良反应情况的差异比较无统计学意义(P>0.05)。结论愈酚伪麻口服溶液治疗儿童急性支气管炎较盐酸氨溴索口服溶液能更快地改善患儿的临床症状,且不良反应较少。

Objective To compare and analyze the clinical curative effect of between gnaifenesin compound pseudoephedrine hydrochloride and ambroxol hydrochloride oral solution in the treatment of children with acute traeheobronehitis. Methods 297 children with acute tracheobronchitis were randomly divided into the control group （ 149 cases） and the experiment group （ 148 cases）. The experi- ment group was treated with guaifenesin compound pseudoephedrine hydrochloride oral solution, and the control group was treated with am- broxol hydroehloride oral solution. The course of treatment was one week. The curative effect and the adverse reactions were eompared be- tween the two groups. Results The improvement was more pronounced in the experiment group than in the control group after the treat- ment （P 〈0. 05）. One week after the treatment, the total effective rate was 90.5% in the experiment group and 79. 2% in the control group respectively. There was no significant difference of the incidence of the adverse reactions between the two groups （ P 〉 0.05 ）. Con- dusion Guaifenesin compound pseudoephedrine hydroehloride oral solution has a better clinical curative effect than ambroxol hydroehlo- ride oral solution in the treatment of children with acute tracheobronchitis, which can improve the clinical symptoms with less adverse reac- tions.