阻塞性睡眠呼吸暂停低通气综合征与脑梗塞患者脑出血的相关性研究

Correlation study between obstructive sleep apnea hyperventilation syndrome and patients with cerebral infarction of cerebral hemorrhage

目的探究并分析阻塞性睡眠呼吸暂停低通气综合征(OSAHS)与脑梗塞患者脑出血的相关性。方法我院收治的OSAHS合并脑出血患者45例,将其作为本次的研究对象,作为观察组;将同期入院的45例非OSAHS的脑出血患者作为对照组。观察并比较两组患者的各项指标情况、昏迷程度及预后。结果与对照组比较,观察组患者的MAP、GLU、LDL-C、Fg、HCT均较高,但氧饱和度低;观察组和对照组重度昏迷的人数分别占55.56%、20.00%,观察组昏迷情况较对照组严重,观察组的无效人数占71.11%,对照组占22.22%,观察组预后较对照组差,P<0.05。结论合并OSAHS的脑梗塞患者更易发生脑出血,且患者的昏迷程度较重,预后较差,OSAHS是导致脑出血的重要危险因素。

Objective To explore and analyze the correlation between obstructive sleep apnea hyperventilation syndrome （OS- AHS） and patients with cerebral infarction of cerebral hemorrhage. Methods 45 OSAHS patients complicated with cerebral hemorrhage were selected as the observation group, and 45 non-OSAHS patients with cerebral hemorrhage were taken as the control group. The related indexes, the coma degree and prognosis were observed and compared between the two groups. Results The levels of MAP, GLU, LDL- C, Fg and HCT were obviously higher in the observation group than in the control group, but the oxygen saturation was lower in the obser- vation group than in the control group. The rate of severe coma was 55.56% and 20. 00% respectively in the observation group and in the control group. The invalid rate was 71.11% and 22.22% respectively in the observation group and in the control group. The prognosis was worse in the observation group than in the control group （ P 〈 0.05 ）. Conclusion The OSAHS patients complicated with cerebral in- farction are easier to have cerebral hemorrhage with severe coma and bad prognosis. Therefore, OSAHS is a high risk factor causing cere- bral hemorrhage.