期刊文献+

缺血再灌注时的胰岛素抵抗现象

Phenomenon of insulin resistance of ischemic reperfusion
原文传递
导出
摘要 胰岛素抵抗是2型糖尿病、冠心病、高血压等慢性疾病的共同机制,以前胰岛素抵抗的研究主要关注于与这些慢性病之间的联系。近年来,胰岛素抵抗与缺血再灌注间的研究逐渐成为新点、热点之一,与患者的预后密切相关。本文根据文献报道,对两者之间的关系作一综述。 Ischemic reperfusion is the common mechanism of some chronic diseases such as type 2 diabetes, coronary heart disease, hypertension, and so on. Previous studies of insulin resistance is mainly focused on the re-lationships of these chronics, while now, in recent years, the research between the insulin resistance and ischemie reperfusion has gradually beeome one of the new and hot points, closely related to the patient's prognosis. In this pa-per, we will review the insulin resistance and ischemic reperfusion aceording to the reported literature review.
出处 《国际外科学杂志》 2013年第7期481-485,共5页 International Journal of Surgery
基金 国家自然科学基金项目(No.81170420)
关键词 胰岛素抗药性 再灌注损伤 糖尿病 PI3K-AKT Insulin resistance Renerfusion iniurv Diabetes mellitus PI3K-AKT
  • 相关文献

参考文献36

  • 1窦梅,马爱国.胰岛素抵抗主要原因及机制的研究进展[J].国外医学(卫生学分册),2009,36(3):174-179. 被引量:89
  • 2方军,张应天.危重病人的高血糖症及处理[J].国际外科学杂志,2006,33(6):451-455. 被引量:15
  • 3Gravlee GP, Davis RF, Utley JR. Cardiopulmonary bypass: principlesand practice[M]. Baltimore: williams & wilkins, 1993 ; 513-519.
  • 4Videla LA. Oxidative stress signaling underlying liver disease andhepatoprotective mechanisms[ J]. World J Hepatol,2009,1(1):72-78.
  • 5张猛,陈曼娥.急性脑缺血高血糖与胰岛素抵抗的实验研究[J].中国危重病急救医学,1999,11(3):135-137. 被引量:19
  • 6Engbersen R, Riksen NP, Mol MJ, et al. Improved resistance toischemia and reperfusion, but impaired protection by ischemic pre-conditioning in patients with type 1 diabetes mellitus : a pilot study[J]. Cardiovasc Diabetol, 2012,11: 124.
  • 7Prakash P, Khanna V,Singh V, et al. Atorvastatin protects againstischemia- reperfusion injury in fructose-induced insulin resistantrats[ J]. Cardiovasc Drugs Ther, 2011,25(4) : 285-297.
  • 8Kantor PF,Dyck JR,Lopaschuk GD. Fatty acid oxidation in thereperfused ischemic heart[J]. Am J Med Sci, 1999, 318(1) : 3-14.
  • 9Depre C, Vanoverscheld LJ, Taegtmeyer H. Glucose for the heart[J]. Circulation, 1999,99(4) ; 578-588.
  • 10Boudina S, Abel ED. Diabetic cardiomyopathy revisited[ J ]. Cir-culation, 2007,115(25) : 3213-3223.

二级参考文献138

共引文献156

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部