囊袋张力环在马凡综合征晶状体半脱位术后防治后发性白内障的应用

Prevention of after-cataract by application of heparin treatment of capsular tension ring in Marfan syndrome and subluxation of lens

目的: 探讨肝素处理的晶状体囊袋张力环应用于马凡综合征合并晶状体半脱位的患者,预防术后发生后发性白内障方面的效果。方法: 将34例56眼患者随机分为试验组和对照组,试验组术前将肝素12500U加入500mL乳酸林格氏液中作为冲洗液,囊袋张力环用肝素原液浸泡20min;对照组乳酸林格氏液中不加任何药物,囊袋张力环也不用肝素浸泡。术后观察患者眼压、前房反应、角膜水肿、人工晶状体位置、后囊膜混浊情况。结果: 试验组总后囊混浊率13.3%,对照组69.2%,差异有统计学意义(P<0.01),试验组前房反应明显轻于对照组(P<0.01),角膜水肿及眼压两组无明显差别。结论: 植入肝素处理的囊袋张力环对马凡综合征晶状体半脱位患者,在术后预防后囊膜混浊,提高术后视力恢复有重要应用价值。

·AIM： To investigate the effect of heparin treatment on capsular tension ring （CTR） in the prevention of after- cataract postoperative patients with Marfan syndrome and subluxation of lens. · METHODS： Totally 34 cases （56 eyes） were divided randomly into experimental and control groups. Preoperative heparin 12500 units was added to 500mL Ringer＇s infusion, and CTR was dealt with heparin stock solution soak for 20 minutes in experimental group; there was no any drugs in the control group＇s solution, and CTR was not dealt with heparin. Postoperative lOP, anterior chamber reaction, corneal edema, IOL position, posterior capsular opacification were observed. ·RESULTS： There was statistically significant difference in the posterior capsular opacification between the heparin group （13.3%） and the contral group no-heparin （69.2%） （ P 〈 0. 01 ）. In addition, anterior chamber reaction of the experimental group was significantly lighter than the control group. However, no significant differences were found between the two groups in lOP and corneal edema.· CONCLUSION： The present results indicate that there is the preventive effect on posterior capsular opacification by CTR soaked in heparin in postoperative patients with Marfan syndrome and subluxation of lens, thus contributing to the recovery of visual function.