近视眼角膜横径和前房深度及前房体积相关因素分析

Analysis of influence factors on anterior chamber volume by corneal horizontal diameter and anterior chamber depth

目的: 分析近视患者角膜横径和前房深度的相关影响因素,进一步探讨前房体积的影响因素。方法: 随机收集241例482眼6～47岁近视患者,男124例248眼,女117例234眼。采用OrbscanⅡZ角膜地形图测量角膜横径和前房深度并应用SPSS17.0统计软件对其相关影响因素进行分析,建立数学模型探讨前房体积影响因素。结果: 角膜横径和前房深度平均值为11.69±0.51,3.04±0.30mm,男性、女性角膜横径和前房深度平均值分别为11.74±0.49,11.64±0.53,3.07±0.30,3.02±0.29mm,性别差异具有统计学意义(t=-2.265,-1.971;P=0.024,0.048),男性角膜横径和前房深度均大于女性。角膜横径和前房深度分别与年龄呈负相关(r=-0.260,-0.246;P=0.00,0.00),与等效球镜度无相关性(r=-0.057,0.067;P=0.210,0.142),角膜横径与前房深度呈正相关(r=0.297;P=0.00),回归方程Y=1.025+0.173X(Y代表前房深度,X代表角膜横径,F=46.440,P=0,R2=0.088)。结论: 近视眼患者的角膜横径和前房深度二者之间呈正相关。角膜横径、前房深度及前房体积男性大于女性,均与年龄呈负相关,与近视等效球镜度数无关。

·AIM： To investigate the horizontal diameter （CHD） （ACD） and discuss the chamber volume （ACV）. correlative factors of corneal and anterior chamber depth affecting factors of anterior ·METHODS： A total of 241 cases （482 eyes） of myopia aged 6-47 years were collected on randomly. There were 124 （248 eyes） male subjects and 117 （234 eyes） female subjects. CHD and ACD were measured with the Orbscan Ⅱ Z system, and each measurement was repeated three times. SPSS 17. 0 software was used to analyze the correlation data. Mathematical model was set up to research anterior chamber volume. ·RESULTS： The average of CHD is （11.69±0.51）mm, with diameter of （11.74±0.49）mm in male and （11.64±0.53） mm in female. The average of ACD was （3. 04±0.30）mm, with depth of （3.07±0.30）mm in male and （3.02±0.29） in female. Differences in gender of CHD and ACD were significant in the t-test for independent samples （ t= -2. 265, -1. 971 ; P= 0. 024, 0.05）, these size of male were both larger than that of female. Through person correlation analysis, a negative correlation wasfound between CHD and age, ACD and age （r= -0. 260, -0. 246; P= 0, 0）; a positive correlation was found between CHD and ACD （ r= 0. 297; P= 0）, the regression equation between CHD and ACD in myopia population was Y=1. 025 ＋ 0.173X （F=46.440,P=0, R2=0.088）, where Y represents ACD and X represents CHD · CONCLUSION： There are statistically significant difference between male and female in CHD, ACD and ACV. The size of these in male is larger than in female. The CHD is positively correlated with the ACD, and CHD, ACD and ACV are negatively correlated with age and are not associated with the degree of myopia.