糖尿病黄斑水肿相关因素分析

Analysis on related factors of diabetic macular edema

目的:探讨糖尿病黄斑水肿(diabetic macular edema,DME)与糖尿病病程和视力之间的关系。方法: 回顾性分析40例40眼荧光素眼底血管造影(fluorescence fundus angiography,FFA)及光学相干断层扫描(optical coherence tomography,OCT)确诊的DME患者的检查结果、糖尿病病程和视力等临床资料。分析各种类型DME与以上相关因素的关系。结果: DME患者40例40眼中,局限型DME14眼(35%),弥漫型20眼(50%),囊样水肿6眼(15%)。患者的视力与DME的类型具有显著相关性(r=-0.835,P=0.000),黄斑囊样水肿较局限型水肿对视力的损害更严重。糖尿病病程与DME的类型具有显著相关性(r=0.472,P=0.002)。结论: DME与糖尿病病程、视力均存在显著相关性。

·AIM： To explore the relationship between diabetic macular edema （DME） and diabetic duration with visual acuity. ~ METHODS： The clinical material examination results, diabetic duration and visual acuity on 40 DME patients diagnosed by fundus fluorescein angiography （FFA） and optical coherence tomography （OCT） method were analyzed in this retrospective study. The relationship between various types of DME and above mentioned factors was also analyzed. ·RESULTS： Among 40 DME patients, 14 eyes （35%）were focal DME, diffuse DME in 20 eyes （50%） and cystoid macular edema in 6 eyes （15%）. Significant correlations existed between the visual loss and the types of DME （r= -0.835, P=0.000）. There was more damage to the visual acuity of patients with macular cystoid edema than those with focal DME. The diabetic duration was closely related to the types of DME （ r= 0. 472, P= 0. 002）.·CONCLUSION： The DME are closely related to diabetic duration and visual acuity.