自体角膜缘干细胞移植治疗维吾尔族翼状胬肉的疗效

Treatment efficacy of autologous limbal stem cell transplantation for pterygium in Uygur

目的: 观察翼状胬肉切除联合自体角膜缘干细胞移植治疗维吾尔族翼状胬肉患者的效果。方法: 维吾尔族患者翼状胬肉163例180眼,采用手术显微镜下翼状胬肉切除联合角膜缘干细胞的结膜瓣移植术,术后观察视力及翼状胬肉复发情况。结果: 翼状胬肉患者163例180眼成功进行翼状胬肉切除联合自体角膜缘干细胞移植术,随访6～48mo,术后12mo内无复发病例;18mo复发1眼(0.6%);24mo复发6眼(3.3%);48mo复发9眼(5%)。163例180眼中16眼复发,复发胬肉较薄,充血轻。本组复发率为8.9%,余未发现复发及复发倾向。结论: 翼状胬肉切除联合自体角膜缘干细胞移植术治疗翼状胬肉并发症少、复发率低,是新疆维吾尔族翼状胬肉患者较为适当的手术方式。

·AIM： To observe the efficacy of pterygium excision combined with autologous limbal stem cell transplantation for pterygium in Uygur.·METHODS： A total of 163 Uighur cases （180 eyes） with pterygium underwent pterygium excision combined with limbal stern cell transplantation. Recurrence rate of pterygium was recorded after surgery.·RESULTS： All 163 cases got successfully surgery. And they were followed up for 6- 48 months with no pterygium recurrent 12- month after surgery, 1 eye （0.6%）, 6 eyes （3.3%） and 9 eyes （5%） recurred at 18, 24 and 48 months, respectively. The total recurrence rate was 8.9% （16/180）. ·CONCLUSION： Pterygium excision combined with autologous limbal stem cell transplantation is an ideal surgical method for pterygium in Uygur, for its fewer complications and low recurrence rate.