期刊文献+

Discrimination of signal oscillations in the in vitro olfactory bulb with microelectrode array 被引量:1

Discrimination of signal oscillations in the in vitro olfactory bulb with microelectrode array
原文传递
导出
摘要 The aim of the present study was to investigate the electrophysiological characteristics of the different layers of the olfactory bulb (OB). We used an in vitro OB slice coupled onto a microelectrode array (MEA) for simultaneous detection of spontaneous activities of OB neurons at different sites. Different frequency oscillations dominated the different layers of the OB slice, and the gamma frequency oscillations mainly appeared in the glomerular layer. The waves consisted of negative, positive, and bidirectional spikes, and were distributed at the different layers of the OB slice. Thus, combination of the OB slice with MEA is a useful technique for identifying signal oscillations by multi-site synchronous measurement, and will allow further studies on olfactory information coding and processing function. The aim of the present study was to investigate the electrophysiological characteristics of the different layers of the olfactory bulb (OB). We used an in vitro OB slice coupled onto a microelectrode array (MEA) for simultaneous detection of spontaneous activi- ties of OB neurons at different sites. Different frequency oscillations dominated the different layers of the OB slice, and the gam- ma frequency oscillations mainly appeared in the glomerular layer. The waves consisted of negative, positive, and bidirectional spikes, and were distributed at the different layers of the OB slice. Thus, combination of the OB slice with MEA is a useful tech- nique for identifying signal oscillations by multi-site synchronous measurement, and will allow further studies on olfactory in- formation coding and processing function.
出处 《Chinese Science Bulletin》 SCIE EI CAS 2013年第24期3015-3018,共4页
基金 supported by the National Natural Science Foundation of China (81027003) the Research Fund for the Doctoral Program of Ministry of Education of China (20120101130011)
关键词 微电极阵列 低频振荡 信号 嗅球 体外 电生理特性 自发活动 同时检测 olfactory bulb slice, signal oscillation discrimination in vitro, microelectrode array
  • 相关文献

参考文献15

  • 1Singer W, Gray C M. Visual feature integration and the temporal correlation hypothesis. Annu Rev Neurosci, 1995, 18: 555-586.
  • 2Sanes J N, Donoghue J P. Oscillations in local field potentials of the primate motor cortex during voluntary movement. Proc Natl Acad Sci USA, 1993, 90: 4470-4474.
  • 3Fell J, Klaver P, Lehnertz K, et al. Human memory formation is accompanied by rhinal-hippocampal coupling and decoupling. Nat Neurosci, 2001, 4: 1259-1264.
  • 4Margrie T W, Schaefer A T. Theta oscillation coupled spike latencies yield computational vigour in a mammalian sensory system. J Physiol, 2003, 546: 363-374.
  • 5Kay L M. Theta oscillations and sensorimotor performance. Proc Natl Acad Sci USA, 2005, 102: 3863-3868.
  • 6Lam Y W, Cohen L B, Wachowiak M, et al. Odors elicit three different oscillations in the turtle olfactory bulb. J Neurosci, 2000, 20: 749-762.
  • 7Friedman D, Strowbridge B W. Both electrical and chemical synapses mediate fast network oscillations in the olfactory bulb. J Neurophysiol, 2003, 89: 2601-2610.
  • 8Lagier S, Carleton A, Lledo P M. Interplay between local GABAergic interneurons and relay neurons generates gamma oscillations in the rat olfactory bulb. J Neurosci, 2004, 24: 4382-4392.
  • 9Beshel J, Kopell N, Kay L M. Olfactory bulb gamma oscillations are enhanced with task demands. J Neurosci, 2007, 27: 8358-8365.
  • 10Gire D H, Schoppa N E. Long-term enhancement of synchronized oscillations by adrenergic receptor activation in the olfactory bulb. J Neurophysiol, 2008, 99: 2021-2025.

同被引文献6

引证文献1

二级引证文献8

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部