摘要
为了在改善壳聚糖(CS)抑菌性能的同时提高其强度,将银基蒙脱土(Ag-MMT)在CS的醋酸溶液中通过溶液插层法制备了银基蒙脱土/壳聚糖(Ag-MMT/CS)。在模拟体液环境中测得的银离子释放性能显示Ag-MMT/CS中的银离子可以达到平稳缓慢释放;通过最小抑菌圈法对Ag-MMT/CS进行抑菌性能测试,结果表明,Ag-MMT/CS对金黄色葡萄球菌有良好的抑菌效果,抑菌圈直径可达9.2mm,比CS增大50.6%,抑菌率测试结果显示蒙脱土的加入有助于吸附并杀死更多的细菌;动态热机械分析(DMA)测试结果显示,Ag-MMT/CS的储能模量最高可达3261MPa,比CS提高195%,显示出良好的动态力学性能。
To obtain antibacterial chitosan with improved dynamic mechanic properties, the Ag - MMT was dispersed in chitosan solution dissolving in acetic acid to obtain nano Ag - MMT/CS composite via solution intercalation. The Ag＋ ion can be released steady and slowly from Ag - MMT/CS in vitro release test in simulated fluid. The bacterial inhibition zone diameter of Ag - MMT/CS is 9.2 mm, which is 50.6%larger than that of CS, the result shows Ag -MMT/CS＇s good antibacterial activity against Staphylococcus aureus. And the inhibition ratio test result suggests the significant surface area and adsorption capacities of MMT help a lot to immobilize more bacteria on the surface and improve the antibacterial activity of Ag - MMT/CS. In the dynamic thermomechanical analysis （DMA） test, the storage modulus of Ag - MMT/CS is 3261 MPa, which exhibits remarkable increase （195 ~ larger than CS） in mechanic property.
出处
《复合材料学报》
EI
CAS
CSCD
北大核心
2013年第4期88-92,共5页
Acta Materiae Compositae Sinica
基金
广东省大学生创新创业训练计划项目(1057312021)
广东药学院大学生创新实验项目
关键词
壳聚糖
银基蒙脱土
抑菌
动态力学性能
复合材料
chitosan
Ag- MMT
antibacterial activity
dynamic mechanic property
composite
