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舒芬太尼的毒理作用及在心血管手术上的应用研究 被引量:2

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摘要 舒芬太尼(sufentanil,Suf)系芬太尼N-4噻吩基衍生物,是一种人工合成的强效阿片类镇痛药,临床应用较为广泛。众多临床研究证实,舒芬太尼脂溶性强,快速分布半衰期和缓慢分布半衰期分别为1.4和17.7 min,与芬太尼相比,消除半衰期更短,清除率更高,毒性作用更低,镇痛作用更强,对中枢神经系统、呼吸系统、心血管系统影响小[1]。
作者 王倩 冯艺
出处 《毒理学杂志》 CAS CSCD 北大核心 2013年第3期222-223,共2页 Journal of Toxicology
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  • 1史春霞,李立环,卿恩明,姜贞,李士通,姚尚龙,郭曲练,王文贤,熊利泽,张铁铮,齐娟,付志俭.舒芬太尼麻醉用于心血管手术的多中心临床研究[J].临床麻醉学杂志,2005,21(8):519-521. 被引量:114
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